GGA3 and M6PR

Number of citations of the paper that reports this interaction (PubMedID 11387475)
128

Data Source:
HPRD (two hybrid, in vitro)

		GGA3	M6PR
Description		golgi associated, gamma adaptin ear containing, ARF binding protein 3	mannose-6-phosphate receptor, cation dependent
Image
GO Annotations	Cellular Component	Golgi Apparatus Trans-Golgi Network Endosome Membrane Early Endosome Membrane Recycling Endosome Membrane	Lysosomal Membrane Endosome Late Endosome Trans-Golgi Network Plasma Membrane Integral Component Of Plasma Membrane Membrane Transport Vesicle Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding ADP-ribosylation Factor Binding Ubiquitin Binding	Transmembrane Signaling Receptor Activity Protein Binding Protein Domain Specific Binding Retromer Complex Binding
	Biological Process	Intracellular Protein Transport Regulation Of Protein Stability Protein Destabilization Endocytic Recycling Protein Localization To Cell Surface Golgi To Plasma Membrane Protein Transport Cellular Protein Metabolic Process Positive Regulation Of Protein Catabolic Process Protein Localization To Lysosome Negative Regulation Of Amyloid-beta Formation	Protein Targeting To Lysosome Receptor-mediated Endocytosis Lysosomal Transport Endosome To Lysosome Transport Secretion Of Lysosomal Enzymes Membrane Organization
Pathways		TBC/RABGAPs MET receptor recycling Amyloid fiber formation	Lysosome Vesicle Biogenesis Retrograde transport at the Trans-Golgi-Network Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs			Alglucosidase alfa 1-3 Sugar Ring of Pentamannosyl 6-Phosphate alpha-D-mannose 6-phosphate
Diseases
GWAS			SjÃ¶gren's syndrome ( 28076899) Total cholesterol levels ( 30275531)
Interacting Genes		29 interacting genes: ADRA2A ADRA2B AFTPH AP1S2 ARAP3 ARF1 ARF3 CDKN2A CLINT1 CLTC CYTH2 EGFR GGA1 GGA2 IGF2R LRP10 M6PR PACS1 RABEP1 RNF11 RPS27A STAB1 SYNRG TBC1D3 TOLLIP TSG101 UBC VPS11 VPS18	6 interacting genes: GGA1 GGA2 GGA3 JUN PLIN3 REN
Entrez ID		23163	4074
HPRD ID		10443	01106
Ensembl ID		ENSG00000125447	ENSG00000003056
Uniprot IDs		A8K6M0 B7Z456 Q9NZ52	F5GX30 P20645
PDB IDs		1JPL 1JUQ 1LF8 1P4U 1WR6 1YD8	1JUQ
Enriched GO Terms of Interacting Partners?
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