CLCC1 and LAMTOR5

		CLCC1	LAMTOR5
Description		chloride channel CLIC like 1	late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Golgi Apparatus Membrane Chloride Channel Complex Intracellular Membrane-bounded Organelle Mitochondria-associated ER Membrane	Lysosome Lysosomal Membrane Cytosol Ragulator Complex
	Molecular Function	Chloride Channel Activity Protein Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding Molecular Adaptor Activity
	Biological Process	Chloride Transmembrane Transport	Cell Cycle Arrest Regulation Of Cell Size Response To Virus Positive Regulation Of Gene Expression Regulation Of Macroautophagy Viral Genome Replication Positive Regulation Of TOR Signaling Negative Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Interleukin-8 Biosynthetic Process Positive Regulation Of NF-kappaB Transcription Factor Activity Protein Localization To Lysosome Cellular Response To Amino Acid Stimulus Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of TORC1 Signaling Positive Regulation Of RNA Polymerase II Regulatory Region Sequence-specific DNA Binding
Pathways			Macroautophagy mTOR signalling mTORC1-mediated signalling Energy dependent regulation of mTOR by LKB1-AMPK TP53 Regulates Metabolic Genes Regulation of PTEN gene transcription Amino acids regulate mTORC1
Drugs
Diseases
GWAS		Fat distribution (HIV) ( 21897333) Recurrent major depressive disorder ( 29317602)
Interacting Genes		7 interacting genes: GHR GPSM2 LAMTOR5 LRIF1 MLXIPL SLC25A24 WDR47	32 interacting genes: ALB ASGR1 BHMT C9 CD74 CEP126 CEP70 CFB CLCC1 DBI EEF1A1 GAPDH GIT1 GPRASP1 LAMTOR4 LRIF1 MAF1 MCPH1 MEOX2 MT2A NCOA6 PDK1 RABIF RBP4 SERPINA1 TAF9 TGFB1 TOP2B TP53 UTP14A YTHDC1 ZBTB16
Entrez ID		23155	10542
HPRD ID		17471	09773
Ensembl ID		ENSG00000121940	ENSG00000134248
Uniprot IDs		A0A024R095 A0A024R0G0 Q96S66	A0A0C4DGV4 O43504
PDB IDs			3MS6 3MSH 5VOK 5X6U 5X6V 5Y38 5Y39 5Y3A 5YK3 6B9X 6EHP 6EHR 6NZD 6U62 6ULG
Enriched GO Terms of Interacting Partners?
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