MYCBP2 and DACH1

		MYCBP2	DACH1
Description		MYC binding protein 2	dachshund family transcription factor 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Microtubule Cytoskeleton Membrane Axon Intracellular Membrane-bounded Organelle	Nucleus Transcription Factor Complex Cytoplasm
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Zinc Ion Binding Ran GTPase Binding Identical Protein Binding Ubiquitin Protein Ligase Activity	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding
	Biological Process	Protein Ubiquitination Branchiomotor Neuron Axon Guidance Central Nervous System Projection Neuron Axonogenesis Positive Regulation Of Protein Ubiquitination Regulation Of Protein Localization Circadian Regulation Of Gene Expression Negative Regulation Of Protein Catabolic Process Neuromuscular Process Regulation Of Cytoskeleton Organization Regulation Of Axon Guidance	Negative Regulation Of Transcription By RNA Polymerase II Suckling Behavior Regulation Of Transcription, DNA-templated Respiratory Gaseous Exchange Cell Proliferation Negative Regulation Of Transcription By Competitive Promoter Binding Negative Regulation Of Cell Migration Regulation Of Nuclear Cell Cycle DNA Replication Negative Regulation Of Transcription, DNA-templated Development Of Primary Female Sexual Characteristics Negative Regulation Of Fibroblast Proliferation Negative Regulation Of Cell Proliferation Involved In Contact Inhibition Negative Regulation Of DNA Biosynthetic Process
Pathways
Drugs
Diseases
GWAS		Chronotype ( 30696823) Iris heterochromicity ( 30895295) Morning person ( 30696823) Preeclampsia ( 23551011) Tourette's syndrome or obsessive-compulsive disorder ( 25158072)	Adverse response to lamotrigine and phenytoin ( 22379998) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Blood urea nitrogen levels ( 31152163 29403010) Chronic kidney disease ( 20383146) Chronotype ( 30696823) Cleft palate ( 30452639) Creatinine levels ( 29403010) Diastolic blood pressure ( 30224653) Estimated glomerular filtration rate ( 31152163 31015462 31451708 30604766) Estimated glomerular filtration rate in non-diabetics ( 31451708) Glomerular filtration rate ( 29403010) Glomerular filtration rate (creatinine) ( 28452372 26831199) Glomerular filtration rate in non diabetics (creatinine) ( 26831199) Longevity ( 20834067) Medication use (diuretics) ( 31015401) Metabolite levels ( 23823483) Obsessive-compulsive disorder ( 22889921) Plateletcrit ( 27863252) Response to fenofibrate (HDL cholesterol levels) ( 27002377) Restless legs syndrome ( 29029846) Serum uric acid levels ( 30993211) Stroke ( 29531354) Total cholesterol levels ( 30498476) Ulna and radius bone mineral density ( 30172743) Urate levels ( 31578528 23263486) Verbal declarative memory ( 25648963) White blood cell count ( 31217584)
Interacting Genes		20 interacting genes: ATP13A2 ATP1B3 CALM1 CDC14B COMMD6 DACH1 EDNRB FBXL3 FBXO45 MAST3 MYC NMNAT2 PTPN12 SCEL SRPK2 UBE2D2 UBE2D3 UBE2L3 YWHAG YWHAQ	31 interacting genes: AHCYL1 AURKA C1orf35 CREBBP EYA1 EYA3 FGF12 FOXO1 JUN MYC MYCBP2 NAGK NCOR1 NF2 NFIC PPIG RNF14 SIN3A SIX1 SMAD1 SMAD3 SMAD4 SOX3 SOX4 STK11 TCF3 TEAD2 TERT U2AF2 UBE2I ZCCHC10
Entrez ID		23077	1602
HPRD ID		10104	16031
Ensembl ID		ENSG00000005810	ENSG00000276644
Uniprot IDs		O75592	Q9UI36
PDB IDs		5O6C	1L8R
Enriched GO Terms of Interacting Partners?
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