SNRNP200 and DHX38

Number of citations of the paper that reports this interaction (PubMedID 25849387)
8

Data Source:
BioGRID (two hybrid)

		SNRNP200	DHX38
Description		small nuclear ribonucleoprotein U5 subunit 200	DEAH-box helicase 38
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP Membrane U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome U2-type Catalytic Step 1 Spliceosome Catalytic Step 2 Spliceosome	Intracellular Nucleus Nucleoplasm Spliceosomal Complex Membrane Catalytic Step 2 Spliceosome
	Molecular Function	RNA Binding RNA Helicase Activity Helicase Activity Protein Binding ATP Binding Identical Protein Binding	RNA Binding RNA Helicase Activity Protein Binding ATP Binding
	Biological Process	Cis Assembly Of Pre-catalytic Spliceosome Spliceosome Conformational Change To Release U4 (or U4atac) And U1 (or U11) MRNA Splicing, Via Spliceosome Osteoblast Differentiation	MRNA Splicing, Via Spliceosome RNA Export From Nucleus MRNA Export From Nucleus MRNA 3'-end Processing
Pathways		mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases		Retinitis pigmentosa (RP)
GWAS			anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Blood protein levels ( 28240269 23696881) Cholesterol, total ( 25961943 20686565) Coronary artery disease ( 29212778) Depression ( 29700475) LDL cholesterol ( 25961943 20686565) Medication use (HMG CoA reductase inhibitors) ( 31015401) Metabolite levels ( 22916037) Serum metabolite levels (CMS) ( 31636271) Urate levels ( 31578528)
Interacting Genes		29 interacting genes: APC BARD1 BCAS2 BRCA1 CHMP1B DHX38 ECT2 EFTUD2 ERG GRB2 HNRNPA1 HSPB1 LSM8 MATR3 MEGF10 PIN1 PRPF3 PRPF31 PRPF8 RNF113A SF3B2 SF3B3 SMNDC1 SNRNP40 SNW1 UBE2I USP19 YWHAB YWHAG	7 interacting genes: CDC40 CSNK2A1 MFAP1 PPP4C SNRNP200 TERF2IP U2AF1
Entrez ID		23020	9785
HPRD ID		03391	05720
Ensembl ID		ENSG00000144028	ENSG00000140829
Uniprot IDs		O75643	Q92620
PDB IDs		2Q0Z 3JCR 4F91 4F92 4F93 4KIT 5O9Z 5URJ 5URK 5URM 5XJC 5YZG 5Z56 5Z57 5Z58 6AH0 6FF7 6ICZ 6QDV 6QW6 6QX9	5YZG
Enriched GO Terms of Interacting Partners?
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