SNRNP200 and SNRNP40

Number of citations of the paper that reports this interaction (PubMedID 26186194)
367

Data Source:
BioGRID (affinity chromatography technology, biochemical, affinity chromatography technology, two hybrid, biochemical)

		SNRNP200	SNRNP40
Description		small nuclear ribonucleoprotein U5 subunit 200	small nuclear ribonucleoprotein U5 subunit 40
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP Membrane U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome U2-type Catalytic Step 1 Spliceosome Catalytic Step 2 Spliceosome	Nucleoplasm U5 SnRNP Small Nucleolar Ribonucleoprotein Complex Cytosol Nuclear Speck U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	RNA Binding RNA Helicase Activity Helicase Activity Protein Binding ATP Binding Identical Protein Binding	RNA Binding Protein Binding
	Biological Process	Cis Assembly Of Pre-catalytic Spliceosome Spliceosome Conformational Change To Release U4 (or U4atac) And U1 (or U11) MRNA Splicing, Via Spliceosome Osteoblast Differentiation	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Processing RNA Splicing
Pathways		mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway	mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs
Diseases		Retinitis pigmentosa (RP)
GWAS			Alcohol dependence ( 23455491) Body mass index ( 26426971 29615537)
Interacting Genes		29 interacting genes: APC BARD1 BCAS2 BRCA1 CHMP1B DHX38 ECT2 EFTUD2 ERG GRB2 HNRNPA1 HSPB1 LSM8 MATR3 MEGF10 PIN1 PRPF3 PRPF31 PRPF8 RNF113A SF3B2 SF3B3 SMNDC1 SNRNP40 SNW1 UBE2I USP19 YWHAB YWHAG	5 interacting genes: ACP5 APP DDR1 DHX16 SNRNP200
Entrez ID		23020	9410
HPRD ID		03391	08481
Ensembl ID		ENSG00000144028	ENSG00000060688
Uniprot IDs		O75643	A0MNP2 Q96DI7
PDB IDs		2Q0Z 3JCR 4F91 4F92 4F93 4KIT 5O9Z 5URJ 5URK 5URM 5XJC 5YZG 5Z56 5Z57 5Z58 6AH0 6FF7 6ICZ 6QDV 6QW6 6QX9	3JCR 5MQF 5O9Z 5XJC 5YZG 5Z56 5Z57 5Z58 6AH0 6AHD 6FF7 6ICZ 6ID0 6ID1 6QDV 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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