TRIM32 and RNF41

Number of citations of the paper that reports this interaction (PubMedID 22493164)
5

Data Source:
BioGRID (two hybrid)

		TRIM32	RNF41
Description		tripartite motif containing 32	ring finger protein 41
Image
GO Annotations	Cellular Component	Cell Nucleus Cytoplasm Cytosol Striated Muscle Myosin Thick Filament	Cytosol Perinuclear Region Of Cytoplasm Endoplasmic Reticulum Tubular Network
	Molecular Function	Transcription Coactivator Activity RNA Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Myosin Binding Tat Protein Binding Translation Initiation Factor Binding Identical Protein Binding Ubiquitin Binding Protein Self-association Ubiquitin Protein Ligase Activity	Ubiquitin-protein Transferase Activity Erythropoietin Receptor Binding Interleukin-3 Receptor Binding Protein Binding Zinc Ion Binding Ral GTPase Binding Protein Domain Specific Binding Receptor Tyrosine Kinase Binding Identical Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Polyubiquitination Tissue Homeostasis Ubiquitin-dependent Protein Catabolic Process Actin Ubiquitination Response To UV Protein Ubiquitination Positive Regulation Of Cell Growth Positive Regulation Of Cell Migration Regulation Of Type I Interferon Production Negative Regulation Of Viral Transcription Response To Tumor Necrosis Factor Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Fat Cell Differentiation Positive Regulation Of Neuron Differentiation Positive Regulation Of Protein Catabolic Process Positive Regulation Of Cell Cycle Positive Regulation Of Proteolysis Muscle Cell Cellular Homeostasis Negative Regulation Of Fibroblast Proliferation Positive Regulation Of Neurogenesis Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Striated Muscle Cell Differentiation Axon Development Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Interleukin-17-mediated Signaling Pathway Positive Regulation Of Chemokine (C-C Motif) Ligand 20 Production Positive Regulation Of Cell Motility	Protein Polyubiquitination Autophagy Negative Regulation Of Cell Proliferation Proteasomal Protein Catabolic Process Negative Regulation Of Cell Migration Regulation Of MAPK Cascade Regulation Of Lymphocyte Differentiation Regulation Of Myeloid Cell Differentiation Positive Regulation Of Protein Catabolic Process Positive Regulation Of DNA-binding Transcription Factor Activity Protein Autoubiquitination Regulation Of Protein Kinase B Signaling Extrinsic Apoptotic Signaling Pathway Negative Regulation Of Mitophagy Regulation Of Establishment Of Cell Polarity Regulation Of Reactive Oxygen Species Metabolic Process Positive Regulation Of Reactive Oxygen Species Metabolic Process
Pathways		Regulation of innate immune responses to cytosolic DNA Antigen processing: Ubiquitination & Proteasome degradation	Downregulation of ERBB2:ERBB3 signaling Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases		Bardet-Biedl syndrome (BBS)
GWAS		Estimated glomerular filtration rate ( 31015462)	Asthma ( 31619474)
Interacting Genes		41 interacting genes: ABI2 ATXN1 CLIP4 GLIS2 HSPA4 IQCB1 IRAK1 KCTD9 MID2 MYCN NDRG2 PDE9A PIAS3 PIAS4 PTCD2 PTPN11 RABAC1 RNF208 RNF41 SCGB1A1 SDCBP STING1 SYT6 TOP1 TRIM23 TRIM27 TRIM5 TRIM72 UBC UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2E3 UBE2N UBE2U UBQLN1 UBQLN4 VPS11 XIAP	39 interacting genes: ADRB2 AP2S1 APP ARL6IP4 ASB6 BIRC6 C1orf109 ERBB3 ERBB4 GDF11 IRS4 ISCA2 KDM3B LEPR LZTS2 MAGEL2 MARK2 MNAT1 MTNR1A MTNR1B NEUROD4 ORMDL2 PPP1R1A RFC4 RNF166 RRM2B SUOX TBATA TRIM32 TRIM8 TSG101 UBASH3A UBASH3B UBE2D3 UBE2K UBE2U UBE2Z USP8 ZAP70
Entrez ID		22954	10193
HPRD ID		03797	11520
Ensembl ID		ENSG00000119401	ENSG00000181852
Uniprot IDs		A0A024R843 Q13049	A0A024RB33 Q9H4P4
PDB IDs		2CT2 5FEY	2FZP 2GWF
Enriched GO Terms of Interacting Partners?
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