CD93 and UBQLN2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		CD93	UBQLN2
Description		CD93 molecule	ubiquilin 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Integral Component Of Membrane Secretory Granule Membrane Specific Granule Membrane Tertiary Granule Membrane Ficolin-1-rich Granule Membrane	Nucleus Cytoplasm Autophagosome Cytosol Plasma Membrane Cytoplasmic Vesicle
	Molecular Function	Complement Component C1q Binding Calcium Ion Binding Protein Binding Carbohydrate Binding Signaling Receptor Activity Transforming Growth Factor Beta Binding	Protein Binding Polyubiquitin Modification-dependent Protein Binding
	Biological Process	Phagocytosis Viral Process Macrophage Activation Neutrophil Degranulation Cell-cell Adhesion	Autophagosome Assembly Ubiquitin-dependent Protein Catabolic Process Regulation Of Macroautophagy Ubiquitin-dependent ERAD Pathway Negative Regulation Of Clathrin-dependent Endocytosis Positive Regulation Of ER-associated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of G Protein-coupled Receptor Internalization Regulation Of Autophagosome Assembly
Pathways		Neutrophil degranulation	Cargo recognition for clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Liver enzyme levels (alanine transaminase) ( 24124411) Obesity-related traits ( 23251661) Venous thromboembolism ( 26888256 31676865)
Interacting Genes		23 interacting genes: ARHGAP15 BAG6 C1QA COL1A1 COL1A2 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 COPS5 F12 GIPC1 KIR2DL2 KNG1 MBL2 MSN MYD88 RANBP1 SCYL1 TENT5A UBQLN2	22 interacting genes: ADRM1 ATXN7 BTRC C1QA CD93 FBXO25 FUS HERC3 HERPUD1 HNRNPA3 HSPA13 MTNR1B PRPF40A PSMA2 PSMA5 PSMD4 RNF11 RPN1 SMURF1 UBC UBE3A UBQLN4
Entrez ID		22918	29978
HPRD ID		00396	02224
Ensembl ID		ENSG00000125810	ENSG00000188021
Uniprot IDs		Q9NPY3	Q9UHD9
PDB IDs			1J8C 2NBV 6MUN
Enriched GO Terms of Interacting Partners?
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