KLRK1 and HCST

Number of citations of the paper that reports this interaction (PubMedID 10426994)
222

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro, in vivo)

		KLRK1	HCST
Description		killer cell lectin like receptor K1	hematopoietic cell signal transducer
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface Integral Component Of Membrane	Plasma Membrane Cell Surface Integral Component Of Membrane
	Molecular Function	Protein Binding Carbohydrate Binding MHC Class Ib Receptor Activity Signaling Receptor Activity MHC Class I Protein Binding	Signaling Receptor Binding Protein Binding Phosphatidylinositol 3-kinase Binding
	Biological Process	Stimulatory C-type Lectin Receptor Signaling Pathway Adaptive Immune Response Signal Transduction Natural Killer Cell Activation Cell Differentiation T Cell Costimulation Positive Regulation Of Interferon-gamma Production Negative Regulation Of GTPase Activity Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Immune Response Defense Response To Gram-positive Bacterium Cellular Response To Lipopolysaccharide Negative Regulation Of Natural Killer Cell Chemotaxis	Protein Phosphorylation Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Immune Response
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell DAP12 interactions DAP12 signaling DAP12 signaling	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Interleukin-1-receptor antagonist levels ( 22205395) Obesity-related traits ( 23251661) Psoriasis ( 28537254)
Interacting Genes		7 interacting genes: HCST MICB RAE1 RAET1E RAET1G TYROBP ULBP3	3 interacting genes: KLRK1 PIK3R1 SPOP
Entrez ID		22914	10870
HPRD ID		17240	04971
Ensembl ID		ENSG00000213809	ENSG00000126264
Uniprot IDs		A0A024RAP8 P26718	Q9UBK5
PDB IDs		1HYR 1KCG 1MPU 4PDC 4S0U
Enriched GO Terms of Interacting Partners?
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