HCST and KLRK1

Number of citations of the paper that reports this interaction (PubMedID 10426994)
222

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro, in vivo)

		HCST	KLRK1
Description		hematopoietic cell signal transducer	killer cell lectin like receptor K1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface Integral Component Of Membrane
	Molecular Function	Signaling Receptor Binding Protein Binding Phosphatidylinositol 3-kinase Binding	Protein Binding Carbohydrate Binding MHC Class Ib Receptor Activity Signaling Receptor Activity MHC Class I Protein Binding
	Biological Process	Protein Phosphorylation Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Immune Response	Stimulatory C-type Lectin Receptor Signaling Pathway Adaptive Immune Response Signal Transduction Natural Killer Cell Activation Cell Differentiation T Cell Costimulation Positive Regulation Of Interferon-gamma Production Negative Regulation Of GTPase Activity Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Immune Response Defense Response To Gram-positive Bacterium Cellular Response To Lipopolysaccharide Negative Regulation Of Natural Killer Cell Chemotaxis
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell DAP12 interactions DAP12 signaling DAP12 signaling
Drugs
Diseases
GWAS			Blood protein levels ( 28240269) Interleukin-1-receptor antagonist levels ( 22205395) Obesity-related traits ( 23251661) Psoriasis ( 28537254)
Interacting Genes		3 interacting genes: KLRK1 PIK3R1 SPOP	7 interacting genes: HCST MICB RAE1 RAET1E RAET1G TYROBP ULBP3
Entrez ID		10870	22914
HPRD ID		04971	17240
Ensembl ID		ENSG00000126264	ENSG00000213809
Uniprot IDs		Q9UBK5	A0A024RAP8 P26718
PDB IDs			1HYR 1KCG 1MPU 4PDC 4S0U
Enriched GO Terms of Interacting Partners?
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