ADGRL1 and ANKS1A

Number of citations of the paper that reports this interaction (PubMedID 10958799)
19

Data Source:
HPRD (two hybrid)

		ADGRL1	ANKS1A
Description		adhesion G protein-coupled receptor L1	ankyrin repeat and sterile alpha motif domain containing 1A
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Postsynaptic Density Integral Component Of Membrane Cell Junction Axon Growth Cone Presynaptic Membrane Neuron Projection Synapse	Nucleoplasm Cytosol Neuron Projection
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Latrotoxin Receptor Activity Carbohydrate Binding Cell Adhesion Molecule Binding	Protein Binding Ephrin Receptor Binding
	Biological Process	Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Calcium-mediated Signaling Using Intracellular Calcium Source Positive Regulation Of Synapse Assembly Positive Regulation Of Synapse Maturation	Substrate-dependent Cell Migration Neuron Remodeling Ephrin Receptor Signaling Pathway Regulation Of Ephrin Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS			Coronary artery disease ( 24262325) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Coronary heart disease ( 21378990) Height ( 28552196 23563607 18391951) Non-small cell lung cancer ( 23144319) Obesity-related traits ( 23251661) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for body mass index ( 25673412)
Interacting Genes		9 interacting genes: ANKS1A APC CACNA1A DLG3 DLG4 PSMA3 ROS1 SHANK1 SHANK2	16 interacting genes: ADGRL1 ARAP3 ARHGAP10 DOK3 EGFR ERBB2 ERBB4 KLF15 NHLRC2 PIK3R3 RANBP3 RB1 SMARCD1 TRIT1 UBC YWHAG
Entrez ID		22859	23294
HPRD ID		14305	10610
Ensembl ID		ENSG00000072071	ENSG00000064999
Uniprot IDs		O94910	Q05CP0 Q92625
PDB IDs			2LMR 2MYQ 6F7O
Enriched GO Terms of Interacting Partners?
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