ANKS1A and ARAP3

Number of citations of the paper that reports this interaction (PubMedID 17314030)
15

Data Source:
BioGRID (two hybrid)

		ANKS1A	ARAP3
Description		ankyrin repeat and sterile alpha motif domain containing 1A	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
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GO Annotations	Cellular Component	Nucleoplasm Cytosol Neuron Projection	Ruffle Cytosol Cytoskeleton Plasma Membrane Lamellipodium
	Molecular Function	Protein Binding Ephrin Receptor Binding	GTPase Activator Activity Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Phosphatidylinositol-3,4-bisphosphate Binding Metal Ion Binding
	Biological Process	Substrate-dependent Cell Migration Neuron Remodeling Ephrin Receptor Signaling Pathway Regulation Of Ephrin Receptor Signaling Pathway	Cytoskeleton Organization Signal Transduction Vesicle-mediated Transport Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways			Rho GTPase cycle
Drugs
Diseases
GWAS		Coronary artery disease ( 24262325) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Coronary heart disease ( 21378990) Height ( 28552196 23563607 18391951) Non-small cell lung cancer ( 23144319) Obesity-related traits ( 23251661) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for body mass index ( 25673412)	Cerebral amyloid deposition (PET imaging) ( 26252872) Diffuse large B cell lymphoma ( 25261932) Household income ( 31844048) Lung cancer ( 28604730) Mean arterial pressure ( 27618448) Offspring birth weight ( 31043758)
Interacting Genes		16 interacting genes: ADGRL1 ARAP3 ARHGAP10 DOK3 EGFR ERBB2 ERBB4 KLF15 NHLRC2 PIK3R3 RANBP3 RB1 SMARCD1 TRIT1 UBC YWHAG	10 interacting genes: ANKS1A ARHGEF6 CD2AP CLNK GGA3 INPPL1 PARD6B SAMHD1 SH3KBP1 TNKS2
Entrez ID		23294	64411
HPRD ID		10610	09441
Ensembl ID		ENSG00000064999	ENSG00000120318
Uniprot IDs		Q05CP0 Q92625	Q05CH1 Q8WWN8 Q9H7C1
PDB IDs		2LMR 2MYQ 6F7O	2KG5 2LNW 5JCP 5JD0
Enriched GO Terms of Interacting Partners?
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