COPG1 and RHOQ

Number of citations of the paper that reports this interaction (PubMedID 12134073)
34

Data Source:
HPRD (in vivo)

		COPG1	RHOQ
Description		COPI coat complex subunit gamma 1	ras homolog family member Q
Image
GO Annotations	Cellular Component	Golgi Membrane Cell Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cytosol Membrane COPI Vesicle Coat Transport Vesicle	Cytoplasm Cytosol Cytoskeleton Actin Filament Plasma Membrane Cell Cortex Golgi-associated Vesicle Membrane Cytoplasmic Vesicle Cell Projection Intracellular Membrane-bounded Organelle Membrane Raft Extracellular Exosome
	Molecular Function	Structural Molecule Activity Protein Binding	GTPase Activity Profilin Binding GTP Binding Protein Kinase Binding GBD Domain Binding
	Biological Process	Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To ER Intra-Golgi Vesicle-mediated Transport Protein Secretion Establishment Of Golgi Localization Organelle Transport Along Microtubule	Endocytosis Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Rho Protein Signal Transduction Insulin Receptor Signaling Pathway Regulation Of Cell Shape Cell Migration Cell Projection Assembly Actin Cytoskeleton Organization Cortical Cytoskeleton Organization Cortical Actin Cytoskeleton Organization Cellular Response To Insulin Stimulus Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Transcription By RNA Polymerase II GTP Metabolic Process Positive Regulation Of Glucose Import Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Filopodium Assembly Negative Regulation Of Protein Localization To Plasma Membrane
Pathways		COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic	Translocation of SLC2A4 (GLUT4) to the plasma membrane Rho GTPase cycle RHO GTPases regulate CFTR trafficking
Drugs		S-(Dimethylarsenic)Cysteine
Diseases
GWAS		Height ( 31562340) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		18 interacting genes: ARCN1 ARF1 COPB1 COPE COPG2 COPZ1 COPZ2 DRD1 H2AX PPBP PTGES3 RAB7A RHOQ SACM1L SCYL1 TAPBP TMED10 WBP2	18 interacting genes: CDC42BPG CDC42EP1 CDC42EP2 CDC42EP3 CDC42EP4 COPB1 COPG1 DOCK8 EXOC7 GOPC PARD6A PARD6B PFN1 PRKCI RAPGEF1 TRIP10 TRIP6 WASL
Entrez ID		22820	23433
HPRD ID		09887	05791
Ensembl ID		ENSG00000181789	ENSG00000119729
Uniprot IDs		Q9Y678	D6W5A7 P17081 V9HWD0
PDB IDs		1R4X	2ATX
Enriched GO Terms of Interacting Partners?
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