FHL2 and GLYR1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		FHL2	GLYR1
Description		four and a half LIM domains 2	glyoxylate reductase 1 homolog
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Focal Adhesion Z Disc M Band	Nucleosome Nucleoplasm Cytosol
	Molecular Function	Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Transcription Factor Binding Identical Protein Binding Metal Ion Binding Androgen Receptor Binding	DNA Binding Chromatin Binding Protein Binding Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Nucleosome Binding Methylated Histone Binding Histone Binding NADP Binding NAD Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Osteoblast Differentiation Response To Hormone Regulation Of Lipid Metabolic Process Androgen Receptor Signaling Pathway Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription, DNA-templated Atrial Cardiac Muscle Cell Development Ventricular Cardiac Muscle Cell Development Heart Trabecula Formation Negative Regulation Of Calcineurin-NFAT Signaling Cascade	Positive Regulation Of Histone Acetylation Positive Regulation Of Transcription By RNA Polymerase II Oxidation-reduction Process
Pathways		PPARA activates gene expression
Drugs
Diseases
GWAS		Body fat mass ( 28552196) Household income (MTAG) ( 31844048) Lung cancer in ever smokers ( 28604730) Pulse pressure ( 30224653 30578418)	Cancer ( 29299148) Night sleep phenotypes ( 27126917)
Interacting Genes		98 interacting genes: ADAM17 AK1 APP AR ARHGAP9 ATXN1 BANP BIN1 BLZF1 BMPR2 BRCA1 CAPN1 CARD8 CCDC92 CKM CREBBP CSK CSN2 CTNNB1 DCP1A DPF2 DTX2 DUSP10 E2F1 E2F2 E2F3 E2F4 EP300 ESR1 FHL1 FHL3 FHL5 FOXO1 GLYR1 GNG12 HAND1 HCK HSPB2 ID3 IDH1 IER3 IGFBP5 IKZF4 INCA1 ITGA3 ITGA7 ITGB1 ITGB2 ITGB5 ITGB6 JUP KANK2 KIAA1217 MCM7 MDM2 MYBPC1 NIBAN1 NRF1 PFKM PHB2 PSEN2 PUF60 RAI2 REL REV1 RFX3 RUNX2 SAP30BP SAXO1 SFPQ SIGLEC6 SLC34A1 SMAD2 SMAD3 SMAD4 SP2 SRF STAT3 SUMO1P1 TNFRSF11A TRAF6 TRIM55 TRIM63 TTN WT1 ZBTB16 ZBTB25 ZFP64 ZFYVE9 ZMYM4 ZNF131 ZNF212 ZNF3 ZNF331 ZNF408 ZNF417 ZNF626 ZNF638	9 interacting genes: CCNC CFAP206 EIF1AD FHL2 GEMIN4 H3-4 H3C1 KDM1A NSD3
Entrez ID		2274	84656
HPRD ID		04026	17625
Ensembl ID		ENSG00000115641	ENSG00000140632
Uniprot IDs		Q14192 Q2XQU9 Q6I9R8	D3DUE6 Q49A26 Q9NZ78
PDB IDs		1X4K 1X4L 2D8Z 2MIU	2UYY 4GUR 4GUS 4GUT 4GUU 4HSU 6R1U 6R25
Enriched GO Terms of Interacting Partners?
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