FHL2 and SAXO1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		FHL2	SAXO1
Description		four and a half LIM domains 2	stabilizer of axonemal microtubules 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Focal Adhesion Z Disc M Band	Centriole Cytoskeleton Axonemal Microtubule Motile Cilium Ciliary Basal Body Sperm Flagellum
	Molecular Function	Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Transcription Factor Binding Identical Protein Binding Metal Ion Binding Androgen Receptor Binding	Protein Binding Microtubule Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Osteoblast Differentiation Response To Hormone Regulation Of Lipid Metabolic Process Androgen Receptor Signaling Pathway Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription, DNA-templated Atrial Cardiac Muscle Cell Development Ventricular Cardiac Muscle Cell Development Heart Trabecula Formation Negative Regulation Of Calcineurin-NFAT Signaling Cascade	Cold Acclimation Cell Projection Organization Microtubule Anchoring Positive Regulation Of Cilium Assembly Protein Stabilization Cellular Response To Cold
Pathways		PPARA activates gene expression
Drugs
Diseases
GWAS		Body fat mass ( 28552196) Household income (MTAG) ( 31844048) Lung cancer in ever smokers ( 28604730) Pulse pressure ( 30224653 30578418)	Prudent dietary pattern ( 28644415)
Interacting Genes		98 interacting genes: ADAM17 AK1 APP AR ARHGAP9 ATXN1 BANP BIN1 BLZF1 BMPR2 BRCA1 CAPN1 CARD8 CCDC92 CKM CREBBP CSK CSN2 CTNNB1 DCP1A DPF2 DTX2 DUSP10 E2F1 E2F2 E2F3 E2F4 EP300 ESR1 FHL1 FHL3 FHL5 FOXO1 GLYR1 GNG12 HAND1 HCK HSPB2 ID3 IDH1 IER3 IGFBP5 IKZF4 INCA1 ITGA3 ITGA7 ITGB1 ITGB2 ITGB5 ITGB6 JUP KANK2 KIAA1217 MCM7 MDM2 MYBPC1 NIBAN1 NRF1 PFKM PHB2 PSEN2 PUF60 RAI2 REL REV1 RFX3 RUNX2 SAP30BP SAXO1 SFPQ SIGLEC6 SLC34A1 SMAD2 SMAD3 SMAD4 SP2 SRF STAT3 SUMO1P1 TNFRSF11A TRAF6 TRIM55 TRIM63 TTN WT1 ZBTB16 ZBTB25 ZFP64 ZFYVE9 ZMYM4 ZNF131 ZNF212 ZNF3 ZNF331 ZNF408 ZNF417 ZNF626 ZNF638	18 interacting genes: ACTN2 CRK FAM124A FHL2 FHL3 GLYCTK KIR3DX1 LMO1 LMO2 MVP OSGIN1 POLR1C SMARCB1 SORBS3 STK16 TRIP6 VPS28 ZMYND19
Entrez ID		2274	158297
HPRD ID		04026	16676
Ensembl ID		ENSG00000115641	ENSG00000155875
Uniprot IDs		Q14192 Q2XQU9 Q6I9R8	B3KQ57 F6S232 Q5VZT6 Q8IYX7
PDB IDs		1X4K 1X4L 2D8Z 2MIU
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?