ALDOA and GALNT6

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		ALDOA	GALNT6
Description		aldolase, fructose-bisphosphate A	polypeptide N-acetylgalactosaminyltransferase 6
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cell Nucleus Cytosol Actin Cytoskeleton Membrane Platelet Alpha Granule Lumen M Band I Band Secretory Granule Lumen Sperm Head Extracellular Exosome Tertiary Granule Lumen Ficolin-1-rich Granule Lumen	Golgi Membrane Golgi Apparatus Integral Component Of Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Binding Actin Binding Fructose-bisphosphate Aldolase Activity Protein Binding Cytoskeletal Protein Binding Tubulin Binding Identical Protein Binding Cadherin Binding Fructose Binding	Polypeptide N-acetylgalactosaminyltransferase Activity Carbohydrate Binding Metal Ion Binding
	Biological Process	Platelet Degranulation Fructose Metabolic Process Gluconeogenesis Glycolytic Process ATP Biosynthetic Process Striated Muscle Contraction Actin Filament Organization Binding Of Sperm To Zona Pellucida Regulation Of Cell Shape Fructose 1,6-bisphosphate Metabolic Process Neutrophil Degranulation Muscle Cell Cellular Homeostasis Protein Homotetramerization Canonical Glycolysis	Protein O-linked Glycosylation O-glycan Processing
Pathways		Platelet degranulation Neutrophil degranulation Glycolysis Gluconeogenesis	O-linked glycosylation of mucins
Drugs		Zinc 1,6-Fructose Diphosphate (Linear Form) Dihydroxyacetone phosphate 1,6-DI-O-PHOSPHONO-D-MANNITOL N-(4-CHLOROPHENYL)-3-(PHOSPHONOOXY)NAPHTHALENE-2-CARBOXAMIDE
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Schizophrenia ( 25056061 29483656)
Interacting Genes		26 interacting genes: ADRB2 ALDOB ATP6V1E1 BCAT2 CACNA1A CYTH2 DYNLL1 EGFR FANCA GALNT6 GPD2 HSD17B10 HSPB2 IFNA4 MLH1 MYOC PCNA PIAS4 PLD2 SRPK2 SUMO4 TERF1 TGM2 TRIM63 TUBB XRN1	5 interacting genes: ALDOA FN1 SLC5A6 TAF9 TMEM9
Entrez ID		226	11226
HPRD ID		00070	05512
Ensembl ID		ENSG00000149925	ENSG00000139629
Uniprot IDs		P04075 V9HWN7	Q8NCL4
PDB IDs		1ALD 2ALD 4ALD 5KY6
Enriched GO Terms of Interacting Partners?
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