FANCF and FANCL

Number of citations of the paper that reports this interaction (PubMedID 16720839)
42

Data Source:
BioGRID (pull down, affinity chromatography technology, affinity chromatography technology, imaging technique)

		FANCF	FANCL
Description		FA complementation group F	FA complementation group L
Image
GO Annotations	Cellular Component	Nucleoplasm Fanconi Anaemia Nuclear Complex	Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Nuclear Body Intracellular Membrane-bounded Organelle Fanconi Anaemia Nuclear Complex
	Molecular Function	Molecular_function Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding Ubiquitin Protein Ligase Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Cellular Response To DNA Damage Stimulus Biological_process Interstrand Cross-link Repair	DNA Repair Protein Monoubiquitination Cellular Response To DNA Damage Stimulus Gamete Generation Interstrand Cross-link Repair Regulation Of Cell Proliferation
Pathways		Fanconi Anemia Pathway	Fanconi Anemia Pathway
Drugs
Diseases		Fanconi anemia	Fanconi anemia
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 31453325 20935630) Body mass index variance ( 31453325) Childhood absence epilepsy ( 30531953) Chronotype ( 30696823) Epilepsy ( 25087078 30531953) Feeling miserable ( 29500382) Generalized epilepsy ( 30531953) Hirschsprung disease ( 27702942) Initial pursuit acceleration ( 29064472) Irritable mood ( 29500382) Obesity ( 23563607) Pre-treatment viral load in HIV-1 infection ( 31219150) Response to selective serotonin reuptake inhibitors and depression ( 27622933) Schizophrenia ( 25056061 29483656) Smoking status (ever vs never smokers) ( 30643258) Tea consumption ( 31046077) Type 2 diabetes ( 30718926) Waist circumference ( 25673412) Waist-hip ratio ( 25673412)
Interacting Genes		12 interacting genes: CTBP1 FAAP100 FAAP20 FANCA FANCB FANCC FANCE FANCG FANCL HES1 MARK3 OLFM2	26 interacting genes: ACVR1 BMPR1B CHCHD3 CTBP1 DOCK8 EIF4ENIF1 FAAP100 FANCB FANCD2 FANCF FANCI GGN GRN HES1 IHO1 IKZF3 KIFC3 LZTS2 PCNA RBM45 RIMBP3 SSX2IP TFCP2 TGFBR1 UBE2T UBE2W
Entrez ID		2188	55120
HPRD ID		04589	06997
Ensembl ID		ENSG00000183161	ENSG00000115392
Uniprot IDs		A3KME0 Q9NPI8	Q9NW38
PDB IDs		2IQC	3ZQS 4CCG
Enriched GO Terms of Interacting Partners?
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