ESRRA and PNRC2

Number of citations of the paper that reports this interaction (PubMedID 11574675)
17

Data Source:
HPRD (in vivo, two hybrid)

		ESRRA	PNRC2
Description		estrogen related receptor alpha	proline rich nuclear receptor coactivator 2
Image
GO Annotations	Cellular Component	Nuclear Chromatin Fibrillar Center Nucleus Nucleoplasm Cytoplasm Microtubule Cytoskeleton Intercellular Bridge	P-body Nucleus Nucleoplasm Golgi Apparatus Cytosol
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Steroid Hormone Receptor Activity Nuclear Receptor Activity Steroid Binding Protein Binding Zinc Ion Binding Protein Domain Specific Binding Sequence-specific DNA Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Mitochondrion Organization Intracellular Receptor Signaling Pathway Response To Estradiol Regulation Of Cell Proliferation Steroid Hormone Mediated Signaling Pathway Regulation Of Osteoblast Differentiation Regulation Of Osteoclast Differentiation Positive Regulation Of Transcription By RNA Polymerase II Cartilage Development Positive Regulation Of Cellular Response To Insulin Stimulus	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Deadenylation-independent Decapping Of Nuclear-transcribed MRNA
Pathways		PPARA activates gene expression Transcriptional activation of mitochondrial biogenesis Transcriptional activation of mitochondrial biogenesis Nuclear Receptor transcription pathway Regulation of RUNX2 expression and activity Regulation of RUNX2 expression and activity	Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs		Troglitazone Diethylstilbestrol Genistein Afimoxifene beta-Naphthoflavone 1-CYCLOHEXYL-N-{[1-(4-METHYLPHENYL)-1H-INDOL-3-YL]METHYL}METHANAMINE Flavone
Diseases
GWAS		Crohn's disease ( 28067908 21102463) Vitiligo ( 27723757)	Obesity-related traits ( 23251661)
Interacting Genes		31 interacting genes: ADH5 ATXN1 DUT ESR1 ESRRG EXOSC6 FUS GTF2B HDAC8 HIF1A KAT2B LYST MACF1 MAP2K5 NCOA1 NCOA3 NR0B1 NR0B2 NRIP1 NSD1 NXF1 PIAS4 PNRC2 PPARGC1A PRKCD PROX1 PSMC5 SIRT1 SMARCD3 SP1 TNNI2	21 interacting genes: APP AR DCP1A ESR1 ESR2 ESRRA ESRRG FBXO7 GLOD4 HNF4A HNF4G NR5A1 NR5A2 RARA RARG RORA RORB SPAG9 XRCC6 ZBTB16 ZBTB48
Entrez ID		2101	55629
HPRD ID		07210	17871
Ensembl ID		ENSG00000173153	ENSG00000189266
Uniprot IDs		P11474 Q569H8	Q9NPJ4
PDB IDs		1XB7 2PJL 3D24 3K6P	4B6H 5KQ1 5KQ4
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?