HIPK1 and SNIP1

Number of citations of the paper that reports this interaction (PubMedID 15231748)
85

Data Source:
HPRD (two hybrid)

		HIPK1	SNIP1
Description		homeodomain interacting protein kinase 1	Smad nuclear interacting protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol PML Body Nuclear Speck	Nucleus Nucleoplasm Cytosol U2-type Precatalytic Spliceosome
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding	RNA Binding MRNA Binding Protein Binding
	Biological Process	Eye Development Protein Phosphorylation Smoothened Signaling Pathway Positive Regulation Of Cell Proliferation Anterior/posterior Pattern Specification Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Retina Layer Formation Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Peptidyl-tyrosine Phosphorylation Neuron Differentiation Adherens Junction Assembly Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation Of Angiogenesis Embryonic Camera-type Eye Morphogenesis Embryonic Retina Morphogenesis In Camera-type Eye Definitive Hemopoiesis Lens Induction In Camera-type Eye Iris Morphogenesis Endothelial Cell Apoptotic Process Extrinsic Apoptotic Signaling Pathway Regulation Of Signal Transduction By P53 Class Mediator	MRNA Splicing, Via Spliceosome Regulation Of Transcription By RNA Polymerase II I-kappaB Kinase/NF-kappaB Signaling Production Of MiRNAs Involved In Gene Silencing By MiRNA
Pathways		YAP1- and WWTR1 (TAZ)-stimulated gene expression Physiological factors Regulation of TP53 Activity through Phosphorylation
Drugs
Diseases
GWAS		Alopecia areata ( 25608926) Breast cancer ( 23535729) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Heel bone mineral density ( 30598549)	Axial length ( 24144296) Eyebrow thickness ( 26926045)
Interacting Genes		14 interacting genes: ATP13A2 CREBBP DAXX FHL3 GLUL HOXD4 NKX2-5 PARK7 PRPF40A RUNX1 SKIL SNIP1 TP53 UBE2I	48 interacting genes: AKIRIN1 CDK6 CHERP CREBBP DVL2 EIF3C EP300 EVA1B FAF1 GMEB1 HIPK1 HIPK3 JUN MAX MFAP1 MYC NFATC2 OXSM PIAS1 PIAS2 PIAS3 PIAS4 POU3F1 PRPF3 PRPF40A RELA SETDB1 SF3B1 SH3D21 SMAD1 SMAD2 SMAD4 SON SP100 SRPK2 SRRM2 STK40 TDG TNIP1 TOPORS TTC14 UBE2I ZCCHC10 ZCCHC7 ZMYM2 ZMYM5 ZNF451 ZNF496
Entrez ID		204851	79753
HPRD ID		06418	06999
Ensembl ID		ENSG00000163349	ENSG00000163877
Uniprot IDs		A0A024R0H9 B4DZ33 Q86Z02	B1AK66 Q8TAD8
PDB IDs			5Z56 5Z57 5Z58 6FF7
Enriched GO Terms of Interacting Partners?
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