HIPK1

Description		homeodomain interacting protein kinase 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol PML Body Nuclear Speck
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding
	Biological Process	Eye Development Protein Phosphorylation Smoothened Signaling Pathway Positive Regulation Of Cell Proliferation Anterior/posterior Pattern Specification Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Retina Layer Formation Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Peptidyl-tyrosine Phosphorylation Neuron Differentiation Adherens Junction Assembly Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation Of Angiogenesis Embryonic Camera-type Eye Morphogenesis Embryonic Retina Morphogenesis In Camera-type Eye Definitive Hemopoiesis Lens Induction In Camera-type Eye Iris Morphogenesis Endothelial Cell Apoptotic Process Extrinsic Apoptotic Signaling Pathway Regulation Of Signal Transduction By P53 Class Mediator
Pathways		YAP1- and WWTR1 (TAZ)-stimulated gene expression Physiological factors Regulation of TP53 Activity through Phosphorylation
Drugs
Diseases
GWAS		Alopecia areata ( 25608926) Breast cancer ( 23535729) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Heel bone mineral density ( 30598549)
Interacting Genes		14 interacting genes: ATP13A2 CREBBP DAXX FHL3 GLUL HOXD4 NKX2-5 PARK7 PRPF40A RUNX1 SKIL SNIP1 TP53 UBE2I
Entrez ID		204851
HPRD ID		06418
Ensembl ID		ENSG00000163349
Uniprot IDs		A0A024R0H9 B4DZ33 Q86Z02
PDB IDs
Enriched GO Terms of Interacting Partners?
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