STOM and ASIC2

Number of citations of the paper that reports this interaction (PubMedID 15471860)
39

Data Source:
HPRD (in vivo)

		STOM	ASIC2
Description		stomatin	acid sensing ion channel subunit 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Mitochondrion Endoplasmic Reticulum Cytoskeleton Plasma Membrane Integral Component Of Plasma Membrane Membrane Vesicle Azurophil Granule Membrane Specific Granule Membrane Melanosome Membrane Raft Perinuclear Region Of Cytoplasm Extracellular Exosome Tertiary Granule Membrane Blood Microparticle	Plasma Membrane Integral Component Of Plasma Membrane Neuronal Cell Body Dendritic Spine
	Molecular Function	Protein Binding Identical Protein Binding Protein Homodimerization Activity RNA Polymerase Binding	Protein Binding Ligand-gated Sodium Channel Activity Ion Gated Channel Activity
	Biological Process	Neutrophil Degranulation Positive Regulation By Host Of Viral Genome Replication Positive Regulation Of Protein Targeting To Membrane Regulation Of Acid-sensing Ion Channel Activity	Regulation Of Systemic Arterial Blood Pressure By Aortic Arch Baroreceptor Feedback Chemical Synaptic Transmission Central Nervous System Development Peripheral Nervous System Development Phototransduction Sensory Perception Of Sound Response To Acidic PH Monovalent Inorganic Cation Transport Regulation Of Vasoconstriction Ion Transmembrane Transport Regulation Of Ion Transmembrane Transport Protein Localization To Synapse Sodium Ion Transmembrane Transport Regulation Of Membrane Potential Negative Regulation Of Apoptotic Process Sensory Perception Of Sour Taste Detection Of Mechanical Stimulus Involved In Sensory Perception Positive Regulation Of Synapse Assembly
Pathways		Stimuli-sensing channels Neutrophil degranulation	Stimuli-sensing channels
Drugs			Amiloride
Diseases		Hereditary stomatocytosis (HSt); Dehydrated hereditary stomatocytosis (DHS); Overhydrated hereditary stomatocytosis (OHS); Familial pseudohyperkalemia (FP)
GWAS			Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Cerebellum cortex volume ( 31530798) Chronotype ( 30696823) Clopidogrel active metabolite levels ( 28207573) Longevity ( 26912274) Mosquito bite size ( 28199695) Plasma parathyroid hormone levels ( 30134803) Polycystic ovary syndrome ( 30343302) Serum bilirubin levels in metabolic syndrome ( 30621171) Severe gingival inflammation ( 28459102)
Interacting Genes		17 interacting genes: ASIC1 ASIC2 ASIC3 ASS1 CRAT DVL3 FPGS LANCL1 MT2A NUP214 PSMB7 RPL13A RUVBL1 RUVBL2 SLC2A1 STXBP1 VAV2	4 interacting genes: ASIC1 ASIC3 PICK1 STOM
Entrez ID		2040	40
HPRD ID		00585	03471
Ensembl ID		ENSG00000148175	ENSG00000108684
Uniprot IDs		A0A024R882 F8VSL7 P27105	Q16515
PDB IDs
Enriched GO Terms of Interacting Partners?
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