STOM and RUVBL2

Number of citations of the paper that reports this interaction (PubMedID 10524211)
7

Data Source:
BioGRID (pull down)

		STOM	RUVBL2
Description		stomatin	RuvB like AAA ATPase 2
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Mitochondrion Endoplasmic Reticulum Cytoskeleton Plasma Membrane Integral Component Of Plasma Membrane Membrane Vesicle Azurophil Granule Membrane Specific Granule Membrane Melanosome Membrane Raft Perinuclear Region Of Cytoplasm Extracellular Exosome Tertiary Granule Membrane Blood Microparticle	Swr1 Complex Intracellular Nucleus Nucleoplasm Nuclear Euchromatin Cytoplasm Centrosome Cytosol Membrane Nuclear Matrix Ino80 Complex NuA4 Histone Acetyltransferase Complex Extracellular Exosome MLL1 Complex R2TP Complex Ribonucleoprotein Complex
	Molecular Function	Protein Binding Identical Protein Binding Protein Homodimerization Activity RNA Polymerase Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding RNA Polymerase II Core Promoter Sequence-specific DNA Binding TFIID-class Transcription Factor Complex Binding DNA Helicase Activity Transcription Corepressor Activity Protein Binding ATP Binding Beta-catenin Binding ATPase Activity TBP-class Protein Binding Chromatin DNA Binding Identical Protein Binding Protein Homodimerization Activity 5'-3' DNA Helicase Activity ADP Binding Unfolded Protein Binding ATPase Binding
	Biological Process	Neutrophil Degranulation Positive Regulation By Host Of Viral Genome Replication Positive Regulation Of Protein Targeting To Membrane Regulation Of Acid-sensing Ion Channel Activity	Box C/D SnoRNP Assembly DNA Repair DNA Recombination Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Protein Folding Histone Acetylation DNA Duplex Unwinding Cellular Response To UV Positive Regulation Of Histone Acetylation Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation Positive Regulation Of Transcription By RNA Polymerase II Establishment Of Protein Localization To Chromatin Cellular Response To Estradiol Stimulus Transcriptional Activation By Promoter-enhancer Looping Negative Regulation Of Estrogen Receptor Binding Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Telomerase RNA Localization To Cajal Body
Pathways		Stimuli-sensing channels Neutrophil degranulation	Telomere Extension By Telomerase HATs acetylate histones
Drugs			Quercetin
Diseases		Hereditary stomatocytosis (HSt); Dehydrated hereditary stomatocytosis (DHS); Overhydrated hereditary stomatocytosis (OHS); Familial pseudohyperkalemia (FP)
GWAS			Blood protein levels ( 28240269)
Interacting Genes		17 interacting genes: ASIC1 ASIC2 ASIC3 ASS1 CRAT DVL3 FPGS LANCL1 MT2A NUP214 PSMB7 RPL13A RUVBL1 RUVBL2 SLC2A1 STXBP1 VAV2	30 interacting genes: AGR2 APP APPL1 APPL2 ATF2 BCL3 CCDC103 CDKN2A CTNNB1 DPCD EHMT2 EP300 EXOSC10 FBL FDFT1 HDAC1 HDAC4 LIG4 LNX1 MCPH1 MDM2 MYC NDRG1 RUVBL1 STOM TAF9 TBP TERT YWHAQ YY1
Entrez ID		2040	10856
HPRD ID		00585	16070
Ensembl ID		ENSG00000148175	ENSG00000183207
Uniprot IDs		A0A024R882 F8VSL7 P27105	B3KNL2 Q9Y230
PDB IDs			2CQA 2XSZ 3UK6 5OAF 6FO1 6H7X 6HTS 6IGM 6QI8 6QI9
Enriched GO Terms of Interacting Partners?
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