HBZ and HBD

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		HBZ	HBD
Description		hemoglobin subunit zeta	hemoglobin subunit delta
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GO Annotations	Cellular Component	Hemoglobin Complex Haptoglobin-hemoglobin Complex Extracellular Exosome	Cytosol Hemoglobin Complex Haptoglobin-hemoglobin Complex Blood Microparticle
	Molecular Function	Peroxidase Activity Oxygen Carrier Activity Iron Ion Binding Protein Binding Oxygen Binding Heme Binding Haptoglobin Binding Organic Acid Binding	Peroxidase Activity Oxygen Carrier Activity Protein Binding Oxygen Binding Heme Binding Haptoglobin Binding Hemoglobin Alpha Binding Organic Acid Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Oxygen Transport Hydrogen Peroxide Catabolic Process Erythrocyte Maturation Cellular Oxidant Detoxification	Blood Coagulation Oxygen Transport Hydrogen Peroxide Catabolic Process Cellular Oxidant Detoxification
Pathways			Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Body mass index ( 26426971) Early cardiac repolarization ( 31600170) Hemoglobin levels ( 26366553) Mean corpuscular hemoglobin ( 29403010 27863252) Mean corpuscular hemoglobin concentration ( 29403010) Mean corpuscular volume ( 29403010 27863252) Red blood cell count ( 29403010)	Beta thalassemia/hemoglobin E disease ( 20183929) Hematology traits ( 23263863) Hemoglobin levels ( 26366553) Logical memory (delayed recall) in normal cognition ( 29274321) Logical memory (immediate recall) in normal cognition ( 29274321) Mean corpuscular hemoglobin concentration ( 23263863)
Interacting Genes		15 interacting genes: APP DOCK8 FGFR3 HBB HBD HNRNPD IKBKG KHDRBS2 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-9 NOTCH2NLA SP1 UPF2	3 interacting genes: APP HBQ1 HBZ
Entrez ID		3050	3045
HPRD ID		00794	00787
Ensembl ID		ENSG00000130656	ENSG00000223609
Uniprot IDs		P02008	A0N071 P02042
PDB IDs		1JEB 3W4U	1SHR 1SI4
Enriched GO Terms of Interacting Partners?
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