CTTN and ANKZF1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
HPRD (two hybrid)

		CTTN	ANKZF1
Description		cortactin	ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1
Image			No pdb structure
GO Annotations	Cellular Component	Ruffle Podosome Cytoplasm Golgi Apparatus Cytosol Cytoskeleton Actin Filament Plasma Membrane Clathrin-coated Pit Focal Adhesion Cell Cortex Voltage-gated Potassium Channel Complex Postsynaptic Density Lamellipodium Dendrite Growth Cone Site Of Polarized Growth Cortical Cytoskeleton Cortical Actin Cytoskeleton Dendritic Spine Intracellular Membrane-bounded Organelle Postsynaptic Membrane Mitotic Spindle Midzone	Cytoplasm Membrane Cdc48p-Npl4p-Vms1p AAA ATPase Complex
	Molecular Function	Protein Binding Profilin Binding Cadherin Binding Actin Filament Binding	Nucleic Acid Binding Protein Binding Metal Ion Binding
	Biological Process	Intracellular Protein Transport Receptor-mediated Endocytosis Substrate-dependent Cell Migration, Cell Extension Actin Filament Polymerization Regulation Of Axon Extension Regulation Of Actin Filament Polymerization Positive Regulation Of Actin Filament Polymerization Actin Cytoskeleton Reorganization Positive Regulation Of Axon Extension Positive Regulation Of Smooth Muscle Contraction Focal Adhesion Assembly Neuron Projection Morphogenesis Cell Motility Positive Regulation Of Dendritic Spine Morphogenesis Membrane Organization Dendritic Spine Maintenance Lamellipodium Organization Postsynaptic Actin Cytoskeleton Organization Regulation Of Autophagy Of Mitochondrion Negative Regulation Of Extrinsic Apoptotic Signaling Pathway	Ubiquitin-dependent ERAD Pathway Cellular Response To Hydrogen Peroxide Nuclear Protein Quality Control By The Ubiquitin-proteasome System Mitochondria-associated Ubiquitin-dependent Protein Catabolic Process
Pathways		RHO GTPases activate PAKs Clathrin-mediated endocytosis
Drugs
Diseases
GWAS
Interacting Genes		39 interacting genes: ACD ACTA1 ACTG1 ACTR3 ANKZF1 ARHGAP17 ARHGAP8 CASP3 CD2AP CHD3 CTNND1 CTNND2 CTTNBP2 DNM1 DNM2 EGFR FER FGD1 GRB2 HAX1 HDAC6 HIP1R KCNA2 KEAP1 MET MYLK SDC3 SHANK2 SIRT1 SMURF1 SPRR2A SRC SYK TINF2 TJP1 TNK2 TRIM15 WASL WIPF1	9 interacting genes: APP AURKB CA2 CRK CTTN DNAJB11 NRSN2 STAT6 YWHAE
Entrez ID		2017	55139
HPRD ID		01268	07673
Ensembl ID		ENSG00000085733	ENSG00000163516
Uniprot IDs		A0A024R5M3 Q14247 Q53HG7	B8ZZS4 Q9H8Y5
PDB IDs		1X69 2D1X
Enriched GO Terms of Interacting Partners?
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