ELF5 and ACTR2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		ELF5	ACTR2
Description		E74 like ETS transcription factor 5	actin related protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Cytoplasm	Extracellular Region Cell Nucleus Cytoplasm Cytosol Arp2/3 Protein Complex Focal Adhesion Postsynaptic Density Actin Cytoskeleton Membrane Lamellipodium Actin Cap Actin Cortical Patch Azurophil Granule Lumen Site Of Double-strand Break Podosome Core Extracellular Exosome Invadopodium Ficolin-1-rich Granule Lumen
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific	Structural Constituent Of Cytoskeleton ATP Binding Actin Filament Binding
	Biological Process	Ectodermal Cell Fate Commitment Regulation Of Transcription By RNA Polymerase II Cell Differentiation Somatic Stem Cell Population Maintenance Negative Regulation Of Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Mammary Gland Epithelial Cell Differentiation	Establishment Or Maintenance Of Cell Polarity Associative Learning Asymmetric Cell Division Meiotic Chromosome Movement Towards Spindle Pole Cytosolic Transport Meiotic Cytokinesis Arp2/3 Complex-mediated Actin Nucleation Response To Immobilization Stress Cellular Response To Trichostatin A Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Neutrophil Degranulation Response To Ethanol Positive Regulation Of Transcription By RNA Polymerase II Ephrin Receptor Signaling Pathway Spindle Localization Cilium Assembly Positive Regulation Of Dendritic Spine Morphogenesis Membrane Organization Cellular Response To Interferon-gamma Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Double-strand Break Repair Via Nonhomologous End Joining
Pathways			Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation EPHB-mediated forward signaling RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs Neutrophil degranulation Clathrin-mediated endocytosis FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs			N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide (2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-one
Diseases
GWAS		β2-Glycoprotein I (β2-GPI) plasma levels ( 23279374) Blood protein levels ( 28240269) Metabolite levels ( 23823483)	Coronary artery disease ( 29212778) Heel bone mineral density ( 30598549) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) Metabolite levels ( 23823483)
Interacting Genes		8 interacting genes: ACTR2 FRZB NFE2 NRIP2 RPS15A SIRT6 SS18L1 UBQLN4	13 interacting genes: ACTC1 ACTR3 ARPC1B ARPC4 ARPC5 BMP2 ELF5 HCLS1 IQGAP2 SHARPIN WASF1 WASF2 WASL
Entrez ID		2001	10097
HPRD ID		05525	05023
Ensembl ID		ENSG00000135374	ENSG00000138071
Uniprot IDs		A0A087X1W9 A8K443 Q9UKW6	P61160
PDB IDs		1WWX
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?