EIF4B and RPS6KB1

  • Number of citations of the paper that reports this interaction (PubMedID 16763566)
  • 156
  • Data Source:
  • HPRD (in vivo, in vitro)

EIF4B

RPS6KB1

Description eukaryotic translation initiation factor 4B ribosomal protein S6 kinase B1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • C-reactive protein levels ( 30388399)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Chronic lymphocytic leukemia or multiple sclerosis ( 31407831)
  • Crohn's disease ( 28067908)
  • Inflammatory bowel disease ( 23128233)
  • Multiple sclerosis ( 21833088)
  • Obesity-related traits ( 23251661)
  • Triglycerides ( 30275531)
Interacting Genes 16 interacting genes: ACD CASP3 CSNK2A1 EIF3A EIF4E PABPC1 PAK2 POT1 RHOU RPS6KB1 SFN SMAD3 SRPK2 TERF1 TINF2 USP11 61 interacting genes: ACTA1 AKT1 APP BTK CDC42 CDK1 CLEC3B COASY CSNK2A1 CSNK2B CYB5R3 DEPTOR DPPA4 EEF2K EIF3B EIF3F EIF4B EIF4EBP1 EP300 FBXO7 GDI2P1 HTT IRS1 KAT2B KIR3DL1 LYN MAPK1 MAPK3 MAPK8 MAPK9 MAPT MARK2 MTOR MXD1 NCBP1 NEDD4 NEK6 NR1I2 PDK1 PDPK1 PIK3CA PIN1 PIP4K2A POLDIP3 PPP1R9A PPP1R9B PPP2CA RAC1 RBX1 RHEB RPS6 RPTOR SRC STK11 SYK TBK1 TERT TRAF4 URI1 USP11 XPO1
Entrez ID 1975 6198
HPRD ID 04892 10202
Ensembl ID ENSG00000063046 ENSG00000108443
Uniprot IDs B4DRM3 E7EX17 P23588 Q7Z5Y0 P23443
PDB IDs 1WI8 2J76 6FEC 3A60 3A61 3A62 3WE4 3WF5 3WF6 3WF7 3WF8 3WF9 4L3J 4L3L 4L42 4L43 4L44 4L45 4L46 4RLO 4RLP 5WBH 5WBK
Enriched GO Terms of Interacting Partners?
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