RPS6KB1 and EIF4EBP1

  • Number of citations of the paper that reports this interaction (PubMedID 11438723)
  • 13
  • Data Source:
  • HPRD (in vivo)

RPS6KB1

EIF4EBP1

Description ribosomal protein S6 kinase B1 eukaryotic translation initiation factor 4E binding protein 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • C-reactive protein levels ( 30388399)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Chronic lymphocytic leukemia or multiple sclerosis ( 31407831)
  • Crohn's disease ( 28067908)
  • Inflammatory bowel disease ( 23128233)
  • Multiple sclerosis ( 21833088)
  • Obesity-related traits ( 23251661)
  • Triglycerides ( 30275531)
Interacting Genes 61 interacting genes: ACTA1 AKT1 APP BTK CDC42 CDK1 CLEC3B COASY CSNK2A1 CSNK2B CYB5R3 DEPTOR DPPA4 EEF2K EIF3B EIF3F EIF4B EIF4EBP1 EP300 FBXO7 GDI2P1 HTT IRS1 KAT2B KIR3DL1 LYN MAPK1 MAPK3 MAPK8 MAPK9 MAPT MARK2 MTOR MXD1 NCBP1 NEDD4 NEK6 NR1I2 PDK1 PDPK1 PIK3CA PIN1 PIP4K2A POLDIP3 PPP1R9A PPP1R9B PPP2CA RAC1 RBX1 RHEB RPS6 RPTOR SRC STK11 SYK TBK1 TERT TRAF4 URI1 USP11 XPO1 32 interacting genes: AKT1 ATM BUB1 CHTF8 CSNK2A1 CSNK2A2 EIF4E EIF4E2 GSK3B IRAK4 LATS1 LRRK2 MAPK1 MAPK14 MAPKAPK5 MLST8 MTOR MVD PLAT PPP2CA PRKCA PRKDC PTPA REL RHEBL1 RICTOR RORC RPS6KA5 RPS6KB1 RPTOR STK3 TCF4
Entrez ID 6198 1978
HPRD ID 10202 03746
Ensembl ID ENSG00000108443 ENSG00000187840
Uniprot IDs P23443 Q13541
PDB IDs 3A60 3A61 3A62 3WE4 3WF5 3WF6 3WF7 3WF8 3WF9 4L3J 4L3L 4L42 4L43 4L44 4L45 4L46 4RLO 4RLP 5WBH 5WBK 1EJ4 1EJH 1WKW 2JGB 2JGC 2V8W 2V8X 2V8Y 3HXG 3HXI 3M93 3M94 3U7X 4UED 5BXV 5EKV 5NVN 5WBJ 6BCU 6BCX
Enriched GO Terms of Interacting Partners?
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