EIF2B1 and MRPL4

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		EIF2B1	MRPL4
Description		eukaryotic translation initiation factor 2B subunit alpha	mitochondrial ribosomal protein L4
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GO Annotations	Cellular Component	Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 2B Complex Plasma Membrane Membrane	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Large Ribosomal Subunit
	Molecular Function	Translation Initiation Factor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding Identical Protein Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding
	Biological Process	Translational Initiation Regulation Of Translational Initiation Response To Heat Response To Glucose Oligodendrocyte Development Response To Peptide Hormone T Cell Receptor Signaling Pathway	Mitochondrial Translational Elongation Mitochondrial Translational Termination
Pathways		Recycling of eIF2:GDP	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination
Drugs
Diseases		Leukoencephalopathy with vanishing white matter; Vanishing white matter disease; Childhood ataxia with diffuse central nervous system hypomyelination (CACH); Cree leukoencephalopathy (CLE)
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Alanine transaminase levels ( 29403010) Pulse pressure ( 27841878) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		15 interacting genes: ADRA2A ADRA2B ADRA2C ADRB2 ARL4D BZW2 CREBBP EIF2B2 EIF2S1 EIF2S2 EPM2A GORASP2 MRPL4 NTAQ1 RD3	9 interacting genes: CLK2 CSNK2A1 DDX24 ECSIT EIF2B1 EXOSC6 KRTAP4-12 TRIM23 XRN2
Entrez ID		1967	51073
HPRD ID		09458	14759
Ensembl ID		ENSG00000111361	ENSG00000105364
Uniprot IDs		Q14232	A0A024R7C5 Q9BYD3 X6RAY8
PDB IDs		3ECS 6CAJ 6EZO 6K71 6K72 6O81 6O85 6O9Z	3J7Y 3J9M 5OOL 5OOM 6NU2 6NU3
Enriched GO Terms of Interacting Partners?
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