ANO6 and ARID2

		ANO6	ARID2
Description		anoctamin 6	AT-rich interaction domain 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cell Cytosol Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Membrane Chloride Channel Complex Specific Granule Membrane Extracellular Exosome Tertiary Granule Membrane	Nucleoplasm Plasma Membrane
	Molecular Function	Calcium Activated Cation Channel Activity Intracellular Calcium Activated Chloride Channel Activity Voltage-gated Ion Channel Activity Voltage-gated Chloride Channel Activity Protein Binding Phospholipid Scramblase Activity Protein Homodimerization Activity Metal Ion Binding	DNA Binding Protein Binding Metal Ion Binding
	Biological Process	Dendritic Cell Chemotaxis Activation Of Blood Coagulation Via Clotting Cascade Cation Transport Chloride Transport Blood Coagulation Phospholipid Scrambling Positive Regulation Of Bone Mineralization Bleb Assembly Ion Transmembrane Transport Positive Regulation Of Ion Transmembrane Transport Purinergic Nucleotide Receptor Signaling Pathway Bone Mineralization Involved In Bone Maturation Sodium Ion Transmembrane Transport Positive Regulation Of Apoptotic Process Neutrophil Degranulation Negative Regulation Of Cell Volume Pore Complex Assembly Positive Regulation Of Phagocytosis, Engulfment Calcium Activated Phosphatidylserine Scrambling Calcium Activated Phosphatidylcholine Scrambling Calcium Activated Galactosylceramide Scrambling Calcium Ion Transmembrane Transport Positive Regulation Of Monocyte Chemotaxis Phosphatidylserine Exposure On Blood Platelet Chloride Transmembrane Transport Positive Regulation Of Potassium Ion Export Across Plasma Membrane Positive Regulation Of Endothelial Cell Apoptotic Process	Heart Morphogenesis Nucleosome Disassembly Regulation Of Transcription, DNA-templated Negative Regulation Of Cell Proliferation Negative Regulation Of Cell Migration Homeostatic Process Embryonic Organ Development Cardiac Muscle Cell Proliferation Coronary Artery Morphogenesis Positive Regulation Of Double-strand Break Repair Via Homologous Recombination
Pathways		Stimuli-sensing channels Neutrophil degranulation	RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Drugs
Diseases
GWAS		Ankylosing spondylitis ( 22138694) Insomnia ( 29520036) Urate levels in obese individuals ( 25811787) Waist circumference adjusted for body mass index ( 28552196)	Chronotype ( 30696823) Hippocampal atrophy ( 19668339) Intelligence (MTAG) ( 29326435) Morning person ( 30696823) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Triglycerides ( 30275531)
Interacting Genes		9 interacting genes: ALG10B ARID2 C12orf40 CPNE8 GXYLT1 LRRK2 MUC19 PRICKLE1 SLC2A13	6 interacting genes: ANO6 CCNA1 NFYC SMARCA4 SMARCE1 TSC22D2
Entrez ID		196527	196528
HPRD ID		18746	16505
Ensembl ID		ENSG00000177119	ENSG00000189079
Uniprot IDs		B3KX12 Q4KMQ2	Q68CP9
PDB IDs
Enriched GO Terms of Interacting Partners?
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