EGR2 and BPGM

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		EGR2	BPGM
Description		early growth response 2	bisphosphoglycerate mutase
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Intracellular Membrane-bounded Organelle	Cytosol Extracellular Exosome
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Activating Transcription Factor Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Ubiquitin Protein Ligase Binding Transcription Regulatory Region DNA Binding Metal Ion Binding SUMO Ligase Activity HMG Box Domain Binding	Bisphosphoglycerate Mutase Activity Phosphoglycerate Mutase Activity Protein Binding Hydrolase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Protein Export From Nucleus Brain Development Peripheral Nervous System Development Learning Or Memory Rhythmic Behavior Motor Neuron Axon Guidance Schwann Cell Differentiation Protein Sumoylation Facial Nerve Structural Organization Rhombomere 3 Formation Rhombomere 5 Formation Regulation Of Ossification Response To Insulin Brain Segmentation Skeletal Muscle Cell Differentiation Myelination Fat Cell Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Neuronal Synaptic Plasticity Cellular Response To Organic Substance	Carbohydrate Metabolic Process Respiratory Gaseous Exchange Erythrocyte Development Canonical Glycolysis
Pathways		Transcriptional regulation of white adipocyte differentiation Activation of anterior HOX genes in hindbrain development during early embryogenesis NGF-stimulated transcription NGF-stimulated transcription EGR2 and SOX10-mediated initiation of Schwann cell myelination EGR2 and SOX10-mediated initiation of Schwann cell myelination	Glycolysis
Drugs
Diseases		Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy	Anemia due to disorders of glycolytic enzymes, including: Hexokinase (HK) deficiency; Phosphoglycerate kinase 1 (PGK1) deficiency; Triose-phosphate isomerase (TPI) deficiency; Glucose phosphate isomerase (GPI) deficiency; Bisphosphoglycerate mutase (BPGM) deficiency
GWAS		Adventurousness ( 30643258) Alopecia areata ( 25608926) Atopic dermatitis ( 23042114) Ewing sarcoma ( 22327514) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Selective IgA deficiency ( 27723758) Temperament ( 22832960) Triglyceride levels ( 30698716) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Vogt-Koyanagi-Harada syndrome ( 25108386)	Blood protein levels ( 30072576)
Interacting Genes		19 interacting genes: ACP5 BPGM DNMT3L GOLGA2 HCFC1 JPT2 MED31 NAB2 NDUFS2 NFATC1 PDE4DIP RBM15B RIMKLB RPL7L1 SOX10 SOX8 SRA1 UBE2I WWP2	9 interacting genes: AKT1 ATF6 ATP4B CEL EGR2 EHD2 GAPDH GRB2 NEK3
Entrez ID		1959	669
HPRD ID		00551	01961
Ensembl ID		ENSG00000122877	ENSG00000172331
Uniprot IDs		P11161	A0A024R782 P07738
PDB IDs			1T8P 2A9J 2F90 2H4X 2H4Z 2H52 2HHJ 3NFY
Enriched GO Terms of Interacting Partners?
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