E2F6 and ZBTB17

Number of citations of the paper that reports this interaction (PubMedID 23082233)
2

Data Source:
BioGRID (two hybrid)

		E2F6	ZBTB17
Description		E2F transcription factor 6	zinc finger and BTB domain containing 17
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm MLL1 Complex RNA Polymerase II Transcription Factor Complex	Nucleoplasm Protein-containing Complex Protein-DNA Complex
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Transcription Factor Binding Sequence-specific DNA Binding Protein Dimerization Activity	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Core Promoter Binding Transcription Coactivator Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Cycle Negative Regulation Of G0 To G1 Transition	Gastrulation With Mouth Forming Second Ectoderm Development Negative Regulation Of Cell Proliferation IRE1-mediated Unfolded Protein Response Negative Regulation Of Cell Cycle Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cell Cycle Arrest
Pathways		G1/S-Specific Transcription Transcriptional Regulation by E2F6	XBP1(S) activates chaperone genes
Drugs
Diseases
GWAS		Diisocyanate-induced asthma ( 25918132) Sudden cardiac arrest ( 21658281)	Erectile dysfunction ( 30583798) Glomerular filtration rate ( 29403010) Heel bone mineral density ( 30598549) Idiopathic dilated cardiomyopathy ( 21459883)
Interacting Genes		28 interacting genes: APP ARAF BMI1 BRDT CENPU DNMT1 DNMT3L DNTTIP1 E2F1 EPC1 EZH1 EZH2 HMG20B INO80B KRTAP10-7 MDN1 NFYA PCGF6 PIK3R3 RING1 RYBP SMARCA4 TFDP1 TFDP2 ZBTB17 ZBTB32 ZFPM2 ZMYND11	24 interacting genes: BCL6 CDKN2B CREBBP DIS3 DNMT3A E2F6 EP300 ESR1 ESR2 GTF2I HCFC1 HK2 HK3 HSPB1 IRF8 ITGB5 MAX MSX2 MYC MYCN PGR TMPRSS11A TOPBP1 ZBTB7C
Entrez ID		1876	7709
HPRD ID		04251	04968
Ensembl ID		ENSG00000169016	ENSG00000116809
Uniprot IDs		A0A0S2Z3K8 O75461 Q53YM3 Q6Q9Z5	Q13105 Q53EM1
PDB IDs			2LVR 2LVT 2LVU 2M0D 2M0E 2M0F 2N25 2N26 2Q81 3M52 4U2M 4U2N 5ION
Enriched GO Terms of Interacting Partners?
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