E2F4 and ATAD2

Number of citations of the paper that reports this interaction (PubMedID 20855524)
42

Data Source:
BioGRID (affinity chromatography technology, pull down)

		E2F4	ATAD2
Description		E2F transcription factor 4	ATPase family AAA domain containing 2
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GO Annotations	Cellular Component	Nuclear Chromatin Cell Nucleus Nucleoplasm Cytoplasm RNA Polymerase II Transcription Factor Complex	Nucleus Nucleoplasm Extracellular Exosome
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Bacterial-type RNA Polymerase Transcriptional Activator Activity, Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Protein Domain Specific Binding Sequence-specific DNA Binding Protein Dimerization Activity Promoter-specific Chromatin Binding	Chromatin Binding Protein Binding ATP Binding ATPase Activity Histone Binding
	Biological Process	Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription By RNA Polymerase II Epithelial Cell Development Cell Volume Homeostasis DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Blood Circulation Animal Organ Morphogenesis Regulation Of Cell Proliferation Motile Cilium Assembly Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Cycle Centriole Assembly Multi-ciliated Epithelial Cell Differentiation	Chromatin Organization Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Chromatin Silencing Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Transcription of E2F targets under negative control by DREAM complex Transcription of E2F targets under negative control by DREAM complex Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 G0 and Early G1 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest Cyclin E associated events during G1/S transition G1/S-Specific Transcription G1/S-Specific Transcription Cyclin D associated events in G1 Cyclin A:Cdk2-associated events at S phase entry	TFAP2 (AP-2) family regulates transcription of growth factors and their receptors
Drugs
Diseases
GWAS
Interacting Genes		29 interacting genes: AP3S2 ARID3A ATAD2 BRCA1 CHMP2A CHUK FHL2 HCFC1 ID3 IKBKB LRRK2 MFHAS1 MGA NDN NOLC1 PCM1 POLR1D RB1 RBL1 RBL2 RNF144A RYBP SMAD2 SMAD3 SPIB TFDP1 TFDP2 TRRAP XPO1	12 interacting genes: BAG4 BCAR3 CASP8 E2F1 E2F2 E2F3 E2F4 ESR1 H3-4 H4C14 MYC NCOA3
Entrez ID		1874	29028
HPRD ID		02806	10678
Ensembl ID		ENSG00000205250	ENSG00000156802
Uniprot IDs		Q16254	A0A024R9G7 Q6PL18
PDB IDs		1CF7 5TUU	3DAI 4QSP 4QSQ 4QSR 4QSS 4QST 4QSU 4QSV 4QSW 4QSX 4QUT 4QUU 4TT2 4TT4 4TT6 4TTE 4TU4 4TU6 4TYL 4TZ2 4TZ8 5A5N 5A5O 5A5P 5A5Q 5A5R 5A81 5A82 5A83 5EPB 5F36 5F3A 5LJ0 6CPS 6EPJ 6EPR 6EPS 6EPT 6EPU 6EPV 6EPW 6EPX 6HDN 6HDO 6HI3 6HI4 6HI5 6HI6 6HI7 6HI8 6HIA 6HIB 6HIC 6HID 6HIE 6S55 6S56 6S57
Enriched GO Terms of Interacting Partners?
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