DSC3 and PKP3

Number of citations of the paper that reports this interaction (PubMedID 12707304)
51

Data Source:
HPRD (two hybrid, in vivo)

		DSC3	PKP3
Description		desmocollin 3	plakophilin 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Extracellular Region Cytoplasm Plasma Membrane Cell-cell Junction Membrane Integral Component Of Membrane Cell Junction Desmosome	Cornified Envelope Nucleus Nucleoplasm Cytoplasm Plasma Membrane Cell-cell Junction Adherens Junction Cell Junction Desmosome Messenger Ribonucleoprotein Complex
	Molecular Function	Calcium Ion Binding Gamma-catenin Binding	RNA Binding Protein Binding Enzyme Binding Translation Regulator Activity Alpha-catenin Binding Cadherin Binding Cell Adhesion Molecule Binding Cadherin Binding Involved In Cell-cell Adhesion
	Biological Process	In Utero Embryonic Development Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Keratinization Cornification Cell-cell Adhesion	Desmosome Assembly Regulation Of Translation Cell-cell Junction Assembly Positive Regulation Of Gene Expression Keratinization Cornification Protein Localization To Plasma Membrane Cell-cell Adhesion Negative Regulation Of MRNA Catabolic Process
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs
Diseases		Hypotrichosis and recurrent skin vesicles
GWAS		Bronchopulmonary dysplasia ( 23897914) Metabolite levels ( 31628463) Obesity-related traits ( 23251661) Protein quantitative trait loci ( 18464913) Supraventricular ectopy ( 29618737) Type 2 diabetes ( 31049640)
Interacting Genes		6 interacting genes: CTNNB1 DDX10 JUP PKP3 PKP4 UCHL5	9 interacting genes: DSC1 DSC2 DSC3 DSG1 DSG2 DSG3 DSP JUP KRT18
Entrez ID		1825	11187
HPRD ID		02604	05711
Ensembl ID		ENSG00000134762	ENSG00000184363
Uniprot IDs		Q14574	Q9Y446
PDB IDs
Enriched GO Terms of Interacting Partners?
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