DRD3 and RDX

Number of citations of the paper that reports this interaction (PubMedID 14499480)
16

Data Source:
BioGRID (two hybrid)

		DRD3	RDX
Description		dopamine receptor D3	radixin
Image			No pdb structure
GO Annotations	Cellular Component	Cell Plasma Membrane Integral Component Of Plasma Membrane Endocytic Vesicle Synaptic Vesicle Membrane Cell Projection Apical Part Of Cell Dopaminergic Synapse Glutamatergic Synapse GABA-ergic Synapse Integral Component Of Postsynaptic Density Membrane	Ruffle Extracellular Space Plasma Membrane Microvillus Focal Adhesion Apical Plasma Membrane Lamellipodium Filopodium T-tubule Midbody Cortical Actin Cytoskeleton Cleavage Furrow Stereocilium Cell Tip Extracellular Exosome Cell Periphery
	Molecular Function	Dopamine Neurotransmitter Receptor Activity, Coupled Via Gi/Go Adrenergic Receptor Activity Protein Binding Drug Binding Protein Domain Specific Binding D1 Dopamine Receptor Binding Dopamine Binding	RNA Binding Actin Binding Protein Binding Protein Domain Specific Binding Cadherin Binding Protein Kinase A Binding ATPase Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Synaptic Transmission, Dopaminergic Response To Amphetamine Regulation Of Blood Volume By Renin-angiotensin G Protein-coupled Receptor Internalization Cellular Calcium Ion Homeostasis Autophagy G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Cell-cell Signaling Behavior Learning Or Memory Learning Locomotory Behavior Positive Regulation Of Cell Proliferation Visual Learning Response To Toxic Substance Regulation Of Dopamine Secretion Regulation Of Lipid Metabolic Process Negative Regulation Of Sodium:proton Antiporter Activity Positive Regulation Of Cytokinesis Circadian Regulation Of Gene Expression Response To Histamine Social Behavior Gastric Emptying Positive Regulation Of Renal Sodium Excretion Regulation Of Multicellular Organism Growth Response To Cocaine Dopamine Metabolic Process Response To Drug Negative Regulation Of Apoptotic Process Regulation Of Potassium Ion Transport Response To Morphine Regulation Of Circadian Sleep/wake Cycle, Sleep Response To Ethanol Negative Regulation Of Blood Pressure Positive Regulation Of Mitotic Nuclear Division Positive Regulation Of Transcription By RNA Polymerase II Acid Secretion Behavioral Response To Cocaine Behavioral Response To Ethanol Negative Regulation Of Oligodendrocyte Differentiation Arachidonic Acid Secretion Negative Regulation Of Protein Secretion Musculoskeletal Movement, Spinal Reflex Action Negative Regulation Of Cytosolic Calcium Ion Concentration Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Protein Kinase B Signaling Negative Regulation Of Synaptic Transmission, Glutamatergic Prepulse Inhibition Phospholipase C-activating Dopamine Receptor Signaling Pathway Negative Regulation Of Dopamine Receptor Signaling Pathway Positive Regulation Of Dopamine Receptor Signaling Pathway Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Regulation Of Locomotion Involved In Locomotory Behavior Regulation Of Postsynaptic Neurotransmitter Receptor Internalization Negative Regulation Of Voltage-gated Calcium Channel Activity	Regulation Of Cell Shape Regulation Of Cell Size Positive Regulation Of Gene Expression Protein Kinase A Signaling Microvillus Assembly Positive Regulation Of Cell Migration Regulation Of Actin Filament Bundle Assembly Regulation Of Rap Protein Signal Transduction Negative Regulation Of Homotypic Cell-cell Adhesion Negative Regulation Of GTPase Activity Cellular Response To Platelet-derived Growth Factor Stimulus Regulation Of GTPase Activity Apical Protein Localization Establishment Of Protein Localization Negative Regulation Of Cell Size Barbed-end Actin Filament Capping Establishment Of Endothelial Barrier Protein Localization To Plasma Membrane Cellular Response To Thyroid Hormone Stimulus Regulation Of Ruffle Assembly Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Organelle Assembly Positive Regulation Of Protein Localization To Early Endosome Positive Regulation Of Cellular Protein Catabolic Process Negative Regulation Of Adherens Junction Organization Positive Regulation Of Early Endosome To Late Endosome Transport
Pathways		Dopamine receptors G alpha (i) signalling events	Recycling pathway of L1 Recycling pathway of L1
Drugs		Ziprasidone Cabergoline Ropinirole Olanzapine Clozapine Mirtazapine Sulpiride Loxapine Remoxipride Pramipexole Chlorpromazine Haloperidol Amoxapine Lisuride Apomorphine Risperidone Dopamine Pimozide Domperidone Pergolide Bromocriptine Quetiapine Levodopa Aripiprazole Chlorprothixene Paliperidone Yohimbine Methotrimeprazine Iloperidone Rotigotine ACP-104 Cariprazine Mianserin Asenapine Amisulpride Captodiame AS-8112 Pardoprunox Piribedil Tiapride	1D-myo-inositol 1,4,5-trisphosphate
Diseases
GWAS		Chronotype ( 30696823) Feeling hurt ( 29500382) Personality dimensions ( 23903073) Smooth-surface caries ( 24556642)	Cognitive function ( 24684796) Multiple sclerosis ( 31604244)
Interacting Genes		16 interacting genes: CLIC6 DRD1 EEF1B2 EEF1G EPB41 EPB41L1 EPB41L2 FLNA GIPC1 GNAI1 GRB2 MPDZ NCK1 NCS1 RDX USP48	19 interacting genes: ABCC2 ARHGDIA CALM1 CPNE1 CPNE2 CPNE4 DRD3 EZR GNA13 ICAM2 ITGB2 KMT2A L1CAM ROCK1 SLC9A3R1 SLC9A3R2 TSC1 VPS11 VWA5A
Entrez ID		1814	5962
HPRD ID		00540	01534
Ensembl ID		ENSG00000151577	ENSG00000137710
Uniprot IDs		A1A4V4 A8K8E4 E9PCM4 P35462 X5D2G4	B0YJ88 P35241 Q6PKD3
PDB IDs		3PBL
Enriched GO Terms of Interacting Partners?
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