DRD2 and KCNJ6

  • Number of citations of the paper that reports this interaction (PubMedID 12297500)
  • 45
  • Data Source:
  • HPRD (in vivo, in vitro)

DRD2

KCNJ6

Description dopamine receptor D2 potassium inwardly rectifying channel subfamily J member 6
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alcohol consumption ( 31358974)
  • Alcohol consumption (drinks per week) ( 30643258 30679032)
  • Alcohol use disorder ( 30940813)
  • Alcoholic chronic pancreatitis ( 28754779)
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Body mass index ( 26426971)
  • Chronotype ( 30696823)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • General factor of neuroticism ( 30867560)
  • Inferior temporal gyrus volume ( 31530798)
  • Information processing speed ( 25869804)
  • Interferon alpha levels in systemic lupus erythematosus ( 25338677)
  • Mood instability ( 31168069)
  • Neuroticism ( 27089181 29255261)
  • Response to antipsychotic treatment in schizophrenia (working memory) ( 21107309)
  • Schizophrenia ( 28991256 25056061 29483656 30285260)
  • Select biomarker traits ( 17903293)
  • Sleep duration ( 27992416)
  • Systolic blood pressure in sickle cell anemia ( 24058526)
  • Triglycerides ( 30275531)
  • Electroencephalographic traits in alcoholism ( 22554406)
  • Response to placebo treatment in childhood asthma (FVC change) ( 31557306)
  • Rosacea symptom severity ( 29771307)
Interacting Genes 26 interacting genes: ADORA2A CADPS CADPS2 CALM1 CLIC6 EPB41 EPB41L1 FLNA GIPC1 GNAI2 GNAI3 GNAZ GNB5 GRIA2 KCNJ6 KCNJ9 NCS1 NEFM NSF PAWR PPP1R9B SLC6A3 SSTR2 SSTR5 TRPC4 TRPC5 8 interacting genes: ADRB2 BIRC5 DLG1 DRD2 GABBR1 KCNJ3 KCNJ9 XIAP
Entrez ID 1813 3763
HPRD ID 00539 02929
Ensembl ID ENSG00000149295 ENSG00000157542
Uniprot IDs A0A024R3C5 A0A024R3I6 P14416 P48051
PDB IDs 1I15 5AER 6CM4
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?