KCNJ6 and BIRC5

Number of citations of the paper that reports this interaction (PubMedID 15218035)
126

Data Source:
BioGRID (pull down)

		KCNJ6	BIRC5
Description		potassium inwardly rectifying channel subfamily J member 6	baculoviral IAP repeat containing 5
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Plasma Membrane Voltage-gated Potassium Channel Complex	Nuclear Chromosome Chromosome, Centromeric Region Condensed Chromosome Kinetochore Nucleus Nucleoplasm Cytoplasm Cytosol Spindle Microtubule Midbody Chromosome Passenger Complex
	Molecular Function	Inward Rectifier Potassium Channel Activity Protein Binding G-protein Activated Inward Rectifier Potassium Channel Activity	Protein Binding Microtubule Binding Ran GTPase Binding Enzyme Binding Identical Protein Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process Metal Ion Binding Chaperone Binding
	Biological Process	Potassium Ion Transport Regulation Of Ion Transmembrane Transport Potassium Ion Import Across Plasma Membrane	Protein Phosphorylation Apoptotic Process Chromosome Segregation Sensory Perception Of Sound Positive Regulation Of Cell Proliferation Cytokine-mediated Signaling Pathway Protein-containing Complex Localization Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Transcription, DNA-templated Cell Division Mitotic Spindle Assembly
Pathways		Activation of G protein gated Potassium channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion SUMOylation of DNA replication proteins RHO GTPases Activate Formins Interleukin-4 and Interleukin-13 signaling TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain Mitotic Prometaphase Neddylation EML4 and NUDC in mitotic spindle formation
Drugs		Ethanol Halothane	Reserpine Berberine LY2181308
Diseases
GWAS		Electroencephalographic traits in alcoholism ( 22554406) Response to placebo treatment in childhood asthma (FVC change) ( 31557306) Rosacea symptom severity ( 29771307)	Blood trace element (Se levels) ( 23720494) Periodontitis (Mean PAL) ( 24024966)
Interacting Genes		8 interacting genes: ADRB2 BIRC5 DLG1 DRD2 GABBR1 KCNJ3 KCNJ9 XIAP	25 interacting genes: AURKA AURKB AURKC BIRC2 BIRC3 BIRC6 CASP3 CASP7 CASP9 CDCA8 CDK1 CDK4 DIABLO EVI5 FBXL7 H3-4 H3C14 HSP90AA1 INCENP KCNJ6 RAN RASA1 TLE3 XIAP XPO1
Entrez ID		3763	332
HPRD ID		02929	04520
Ensembl ID		ENSG00000157542	ENSG00000089685
Uniprot IDs		P48051	A0A0B4J1S3 H3BLT4 O15392
PDB IDs			1E31 1F3H 1XOX 2QFA 2RAW 2RAX 3UEC 3UED 3UEE 3UEF 3UEG 3UEH 3UEI 3UIG 3UIH 3UII 3UIJ 3UIK 4A0I 4A0J 4A0N 6SHO
Enriched GO Terms of Interacting Partners?
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