DLG3 and EXOC7

Number of citations of the paper that reports this interaction (PubMedID 12738960)
112

Data Source:
BioGRID (pull down)

		DLG3	EXOC7
Description		discs large MAGUK scaffold protein 3	exocyst complex component 7
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytosol Plasma Membrane Bicellular Tight Junction Ionotropic Glutamate Receptor Complex Basolateral Plasma Membrane Cell Junction Growth Cone AMPA Glutamate Receptor Complex Neuronal Cell Body Dendritic Shaft Glutamatergic Synapse Postsynaptic Density, Intracellular Component	Exocyst Microtubule Organizing Center Cytosol Plasma Membrane Membrane Growth Cone Membrane Centriolar Satellite Flemming Body
	Molecular Function	Protein Binding Protein C-terminus Binding Kinase Binding Phosphatase Binding Protein Phosphatase Binding PDZ Domain Binding Ubiquitin Protein Ligase Binding Ionotropic Glutamate Receptor Binding Structural Constituent Of Postsynaptic Density	Protein Binding
	Biological Process	MAPK Cascade Establishment Of Planar Polarity Negative Regulation Of Cell Proliferation Embryo Development Negative Regulation Of Phosphatase Activity Receptor Clustering Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Positive Regulation Of Protein Tyrosine Kinase Activity Receptor Localization To Synapse Cell-cell Adhesion Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Maintenance Of Postsynaptic Density Structure Regulation Of NMDA Receptor Activity	Exocytosis Protein Transport Regulation Of Macroautophagy Regulation Of Entry Of Bacterium Into Host Cell
Pathways		Unblocking of NMDA receptors, glutamate binding and activation Unblocking of NMDA receptors, glutamate binding and activation Ras activation upon Ca2+ influx through NMDA receptor NrCAM interactions Activation of Ca-permeable Kainate Receptor RAF/MAP kinase cascade Neurexins and neuroligins Neurexins and neuroligins Synaptic adhesion-like molecules Assembly and cell surface presentation of NMDA receptors Negative regulation of NMDA receptor-mediated neuronal transmission Long-term potentiation	Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases		Non-syndromic X-linked mental retardation
GWAS
Interacting Genes		40 interacting genes: ABCA1 ADGRL1 APC ATP2B4 CACNG2 CALM1 CNKSR2 CRIPT DLG1 DLG4 DLGAP1 DLGAP3 DLGAP4 ERBB4 EXOC4 EXOC7 GDA GLS2 GRIK2 GRIN1 GRIN2A GRIN2B GRIN2C GUCY1A2 KCNA4 KCNJ12 KCNJ2 KHDRBS1 KIF1B LIN7A LRP2 MAPK12 NLGN1 NLGN2 NLGN3 PTK2B SCN4A SCN5A SEMA4C SYNGAP1	25 interacting genes: AKTIP ARFGEF2 ARPC1A BBS1 BBS2 BBS4 CCDC85B CDC5L DISC1 DLG3 EXOC2 EXOC4 GRIN2B HGS IFT20 KXD1 PRPF19 RALA RHOQ RTN4IP1 SMARCE1 SSC5D TRAF4 USHBP1 ZC3H14
Entrez ID		1741	23265
HPRD ID		02177	16292
Ensembl ID		ENSG00000082458	ENSG00000182473
Uniprot IDs		Q59FY1 Q92796	B4DJ07 B5MCY9 Q63HP7 Q9UPT5
PDB IDs		1UM7 2FE5 2I1N
Enriched GO Terms of Interacting Partners?
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