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FAM9B and GPX1
Number of citations of the paper that reports this interaction (PubMedID
24722188
)
51
Data Source:
BioGRID
(two hybrid)
FAM9B
GPX1
Description
family with sequence similarity 9 member B
glutathione peroxidase 1
Image
No pdb structure
GO Annotations
Cellular Component
Synaptonemal Complex
Nucleoplasm
Cell
Cytoplasm
Mitochondrion
Mitochondrial Matrix
Cytosol
Lewy Body
Molecular Function
Protein Binding
Peroxidase Activity
Glutathione Peroxidase Activity
SH3 Domain Binding
Biological Process
Spermatogenesis
Spermatid Development
Meiotic Cell Cycle
Temperature Homeostasis
Endothelial Cell Development
Negative Regulation Of Inflammatory Response To Antigenic Stimulus
Purine Nucleotide Catabolic Process
Triglyceride Metabolic Process
Glutathione Metabolic Process
Sensory Perception Of Sound
Response To Xenobiotic Stimulus
Response To Symbiotic Bacterium
UV Protection
Response To Selenium Ion
Response To Gamma Radiation
Protein Oxidation
Lipoxygenase Pathway
Response To Hydroperoxide
Regulation Of Mammary Gland Epithelial Cell Proliferation
Cellular Response To Oxidative Stress
Regulation Of Gene Expression, Epigenetic
Vasodilation
Response To Hydrogen Peroxide
Hydrogen Peroxide Catabolic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Skeletal Muscle Tissue Regeneration
Blood Vessel Endothelial Cell Migration
Fat Cell Differentiation
Cell Redox Homeostasis
Skeletal Muscle Fiber Development
Myoblast Proliferation
Interaction With Symbiont
Positive Regulation Of Protein Kinase B Signaling
Heart Contraction
Angiogenesis Involved In Wound Healing
Regulation Of Proteasomal Protein Catabolic Process
Negative Regulation Of Release Of Cytochrome C From Mitochondria
Cellular Oxidant Detoxification
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Supramolecular Fiber Organization
Pathways
Synthesis of 5-eicosatetraenoic acids
Synthesis of 12-eicosatetraenoic acid derivatives
Synthesis of 15-eicosatetraenoic acid derivatives
Detoxification of Reactive Oxygen Species
Purine catabolism
Drugs
Glutathione
Diseases
Anemia due to disorders of glutathione metabolism, including: Glucose-6-phosphate dehydrogenase (G6PD) deficiency; Glutathione peroxidase (GPX) deficiency; Gamma-glutamylcysteine synthetase (GCLC) deficiency; Glutathione synthetase (GSS) deficiency
GWAS
Age at voice drop (
27182965
)
Androgen levels (
22936694
)
Creatinine levels (
29403010
)
Glomerular filtration rate (
29403010
)
Heel bone mineral density (
30598549
28869591
)
Hematocrit (
29403010
)
Hemoglobin (
29403010
)
Male-pattern baldness (
29146897
27182965
)
Metabolite levels (
23823483
)
Blood protein levels (
28240269
)
Crohn's disease (
28067908
21102463
)
Extremely high intelligence (
29520040
)
Household income (MTAG) (
31844048
)
Inflammatory bowel disease (
28067908
23128233
)
Intelligence (MTAG) (
29326435
)
Mood instability (
31168069
)
Sleep duration (short sleep) (
30846698
)
Ulcerative colitis (
28067908
25082827
)
Interacting Genes
123 interacting genes:
ABT1
ACP6
ANKRD36B
AP1M1
ASB6
ATF7
AURKAIP1
BAG6
BARD1
BCL2A1
BET1
BLOC1S2
BYSL
C16orf72
C19orf57
C8orf33
CADPS
CCDC106
CCDC116
CCDC198
CCDC70
CDC23
CDC42EP4
CDCA7L
CENPL
CEP57L1
CEP95
CHRAC1
CLCN1
CMTM6
COL20A1
CSDE1
CWF19L2
DAPK2
DAXX
DENND2D
DGUOK
DNAJC15
DNAJC4
EBNA1BP2
ECH1
EIF3G
ELOA
FAM161A
FASTKD3
FCHSD2
FERD3L
FNDC11
GFOD1
GOPC
GPX1
GSTK1
HNRNPLL
ISCU
LIN7A
LINC02363
LMNA
LNX1
LYRM2
MAB21L3
MFAP1
MOB1A
MORF4L1
MORF4L2
MRPL10
MRPL28
MRPL9
MYG1
MYO15B
NDE1
NDUFB10
NEBL
NOL4
PAGE1
PAGE3
PHYH
PIN4
POLL
PPP1R18
PRPF3
PSMD14
PTRH1
RAB17
RAD51B
RBM17
RBM23
RMND1
RPL9
RSL24D1
RUSC1
SDCBP
SDCBP2
SERPINE2
SFN
SLC16A3
SLPI
SMARCB1
SMN2
SNAP29
SNAP47
SNX20
STK3
SUCLA2
SYT17
TBRG4
TCEA2
TCEANC
TGFBI
TRMT61B
TSG101
TUFM
TXN2
UBE2E2
URB1-AS1
WT1
XRCC4
YARS2
ZCCHC10
ZGPAT
ZNF41
ZNF410
ZNF567
ZNF614
15 interacting genes:
ABL1
ABL2
ACKR2
CAMP
CISH
EBNA1BP2
FAM9B
IDH2
ITGA9
MAPK6
MLH1
MST1R
RHOA
SELENBP1
UQCRC1
Entrez ID
171483
2876
HPRD ID
15955
11749
Ensembl ID
ENSG00000177138
ENSG00000233276
Uniprot IDs
A0A024RBV3
Q8IZU0
A0A2R8Y6B6
P07203
Q7L4Q3
PDB IDs
2F8A
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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