DDX1 and NME7

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		DDX1	NME7
Description		DEAD-box helicase 1	NME/NM23 family member 7
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol Cytoplasmic Stress Granule Membrane Cleavage Body TRNA-splicing Ligase Complex Ribonucleoprotein Complex	Centrosome Cytosol
	Molecular Function	DNA Binding Chromatin Binding Transcription Coregulator Activity RNA Binding RNA Helicase Activity Double-stranded RNA Binding Helicase Activity Nuclease Activity Exonuclease Activity Protein Binding ATP Binding Poly(A) Binding DNA/RNA Helicase Activity	Nucleoside Diphosphate Kinase Activity Protein Binding ATP Binding Metal Ion Binding
	Biological Process	Spliceosomal Complex Assembly Positive Regulation Of Myeloid Dendritic Cell Cytokine Production Double-strand Break Repair TRNA Splicing, Via Endonucleolytic Cleavage And Ligation Regulation Of Translational Initiation Multicellular Organism Development Viral Process DNA Duplex Unwinding Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Response To Exogenous DsRNA Innate Immune Response Defense Response To Virus Nucleic Acid Phosphodiester Bond Hydrolysis Regulation Of Nucleic Acid-templated Transcription Protein Localization To Cytoplasmic Stress Granule	Nucleoside Diphosphate Phosphorylation GTP Biosynthetic Process UTP Biosynthetic Process CTP Biosynthetic Process
Pathways		tRNA processing in the nucleus	Recruitment of mitotic centrosome proteins and complexes Recruitment of NuMA to mitotic centrosomes
Drugs
Diseases
GWAS		Asthma or chronic obstructive pulmonary disease ( 24993907) Blood urea nitrogen levels ( 31152163) Chronic kidney disease ( 22479191) Chronic obstructive pulmonary disease ( 30804561) Estimated glomerular filtration rate ( 31152163 31015462 31451708 30604766) Estimated glomerular filtration rate in non-diabetics ( 31451708) Glomerular filtration rate (creatinine) ( 28452372 26831199) Glomerular filtration rate in non diabetics (creatinine) ( 26831199) Metabolite levels ( 23823483) Pulmonary function ( 21946350) Pulmonary function (smoking interaction) ( 23284291) Urate levels ( 31578528) Wilms tumor ( 22544364)	Coronary artery disease ( 29212778) D-dimer levels ( 21502573) Pulse pressure ( 27841878 30578418) QT interval ( 30679814) Systolic blood pressure ( 27841878 30578418) Venous thromboembolism ( 21980494 22672568)
Interacting Genes		9 interacting genes: APP ATM CSTF2 ESR1 HNRNPK NDRG1 NME7 RELA YWHAQ	28 interacting genes: C1orf189 CCHCR1 CDC42EP2 CEP72 DDX1 FKBP6 FOSL1 GOLGA2 IKZF1 KRT18 LNX1 MAP4K4 MYOT NAB2 NEFL NT5C2 OFD1 REL SHTN1 SYCE1 TCF4 TCHP TNIP1 TRIM27 TUFT1 YWHAQ ZBTB48 ZNF263
Entrez ID		1653	29922
HPRD ID		03158	11394
Ensembl ID		ENSG00000079785	ENSG00000143156
Uniprot IDs		A3RJH1 Q92499	A0A024R8Z7 Q9Y5B8
PDB IDs		4XW3
Enriched GO Terms of Interacting Partners?
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