DDX1 and CSTF2

Number of citations of the paper that reports this interaction (PubMedID 11598190)
26

Data Source:
HPRD (in vitro)

		DDX1	CSTF2
Description		DEAD-box helicase 1	cleavage stimulation factor subunit 2
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol Cytoplasmic Stress Granule Membrane Cleavage Body TRNA-splicing Ligase Complex Ribonucleoprotein Complex	Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex Nuclear Body Cleavage Body
	Molecular Function	DNA Binding Chromatin Binding Transcription Coregulator Activity RNA Binding RNA Helicase Activity Double-stranded RNA Binding Helicase Activity Nuclease Activity Exonuclease Activity Protein Binding ATP Binding Poly(A) Binding DNA/RNA Helicase Activity	RNA Binding MRNA Binding Protein Binding
	Biological Process	Spliceosomal Complex Assembly Positive Regulation Of Myeloid Dendritic Cell Cytokine Production Double-strand Break Repair TRNA Splicing, Via Endonucleolytic Cleavage And Ligation Regulation Of Translational Initiation Multicellular Organism Development Viral Process DNA Duplex Unwinding Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Response To Exogenous DsRNA Innate Immune Response Defense Response To Virus Nucleic Acid Phosphodiester Bond Hydrolysis Regulation Of Nucleic Acid-templated Transcription Protein Localization To Cytoplasmic Stress Granule	MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription MRNA Polyadenylation TRNA Splicing, Via Endonucleolytic Cleavage And Ligation MRNA 3'-end Processing Pre-mRNA Cleavage Required For Polyadenylation
Pathways		tRNA processing in the nucleus	tRNA processing in the nucleus mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS		Asthma or chronic obstructive pulmonary disease ( 24993907) Blood urea nitrogen levels ( 31152163) Chronic kidney disease ( 22479191) Chronic obstructive pulmonary disease ( 30804561) Estimated glomerular filtration rate ( 31152163 31015462 31451708 30604766) Estimated glomerular filtration rate in non-diabetics ( 31451708) Glomerular filtration rate (creatinine) ( 28452372 26831199) Glomerular filtration rate in non diabetics (creatinine) ( 26831199) Metabolite levels ( 23823483) Pulmonary function ( 21946350) Pulmonary function (smoking interaction) ( 23284291) Urate levels ( 31578528) Wilms tumor ( 22544364)
Interacting Genes		9 interacting genes: APP ATM CSTF2 ESR1 HNRNPK NDRG1 NME7 RELA YWHAQ	23 interacting genes: APP BAG6 CEP126 CHD3 CSTF3 DDX1 ECH1 EEF1G ELP1 ERG28 FEZ1 HGS IMMT KAT5 POLR2A SPAG8 SS18L1 SUB1 SYMPK TFG UBQLN1 UBQLN4 ZNF341
Entrez ID		1653	1478
HPRD ID		03158	02652
Ensembl ID		ENSG00000079785	ENSG00000101811
Uniprot IDs		A3RJH1 Q92499	B3V096 B4DUD5 E7EWR4 P33240
PDB IDs		4XW3	1P1T 2J8P
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?