DCX and NFASC

Number of citations of the paper that reports this interaction (PubMedID 12223548)
30

Data Source:
HPRD (in vivo, in vitro)

		DCX	NFASC
Description		doublecortin	neurofascin
Image
GO Annotations	Cellular Component	Cytosol Cytoskeleton Microtubule Microtubule Associated Complex Axoneme Neuron Projection	Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Dendrite Paranodal Junction Node Of Ranvier Paranode Region Of Axon Axon Initial Segment Schwann Cell Microvillus Ficolin-1-rich Granule Membrane
	Molecular Function	Protein Binding Microtubule Binding Protein Kinase Binding	Protein Binding Protein Domain Specific Binding Protein Binding Involved In Heterotypic Cell-cell Adhesion
	Biological Process	Neuron Migration Nervous System Development Central Nervous System Development Axoneme Assembly Intracellular Signal Transduction Photoreceptor Cell Development Retina Development In Camera-type Eye	Protein Localization To Paranode Region Of Axon Axon Guidance Peripheral Nervous System Development Transmission Of Nerve Impulse Paranodal Junction Assembly Heterotypic Cell-cell Adhesion Myelination Neutrophil Degranulation Clustering Of Voltage-gated Sodium Channels Synapse Organization Protein Localization To Juxtaparanode Region Of Axon Protein Localization To Plasma Membrane
Pathways		Neurofascin interactions	Interaction between L1 and Ankyrins Neurofascin interactions Neurofascin interactions Neutrophil degranulation
Drugs
Diseases		Lissencephaly (LIS); Miller-Dieker syndrome (MDLS)
GWAS			Amyotrophic lateral sclerosis (sporadic) ( 24529757) Blood protein levels ( 30072576 29875488 28240269) Clozapine-induced agranulocytosis ( 25187353) Dental caries ( 23064961) Diisocyanate-induced asthma ( 25918132) Disrupted circadian rhythm (low relative amplitude of rest-activity cycles) ( 30120083) General risk tolerance (MTAG) ( 30643258) Mean platelet volume ( 27863252) Regular attendance at a religious group ( 29970889)
Interacting Genes		30 interacting genes: ACD AP1M1 AP2M1 APP CALCOCO2 CDK5 FBXO25 GOLGA2 IKZF1 KIFC3 KRT40 KRTAP10-8 MEOX1 MID2 NFASC PAFAH1B1 POT1 PPP1CA PPP1R9B RBM5 RINT1 SPAG5 SPP1 TERF1 TINF2 TRIM23 TRIM27 TRIM39 USP9X ZBTB5	10 interacting genes: ANK1 CNTNAP1 DCX NRCAM SCN1B SCN3B SCNN1B SDCBP SDCBP2 TNR
Entrez ID		1641	23114
HPRD ID		02127	12372
Ensembl ID		ENSG00000077279	ENSG00000163531
Uniprot IDs		A8K340 O43602	B4DRH7 O94856
PDB IDs		1MJD 2BQQ 2XRP 4ATU 5IKC 5IN7 5IO9 5IOI 5IP4 6FNZ	3P3Y 3P40
Enriched GO Terms of Interacting Partners?
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