DCX and SPAG5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		DCX	SPAG5
Description		doublecortin	sperm associated antigen 5
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Microtubule Microtubule Associated Complex Axoneme Neuron Projection	Kinetochore Condensed Chromosome Kinetochore Cytoplasm Midbody Centriolar Satellite Microtubule Plus-end Mitotic Spindle Mitotic Spindle Pole
	Molecular Function	Protein Binding Microtubule Binding Protein Kinase Binding	Protein Binding Microtubule Binding
	Biological Process	Neuron Migration Nervous System Development Central Nervous System Development Axoneme Assembly Intracellular Signal Transduction Photoreceptor Cell Development Retina Development In Camera-type Eye	Mitotic Sister Chromatid Segregation Spindle Organization Chromosome Segregation Positive Regulation Of Intracellular Transport Cell Division Regulation Of Attachment Of Spindle Microtubules To Kinetochore Protein Localization To Centrosome Regulation Of Metaphase Plate Congression Positive Regulation Of Spindle Assembly
Pathways		Neurofascin interactions
Drugs
Diseases		Lissencephaly (LIS); Miller-Dieker syndrome (MDLS)
GWAS
Interacting Genes		30 interacting genes: ACD AP1M1 AP2M1 APP CALCOCO2 CDK5 FBXO25 GOLGA2 IKZF1 KIFC3 KRT40 KRTAP10-8 MEOX1 MID2 NFASC PAFAH1B1 POT1 PPP1CA PPP1R9B RBM5 RINT1 SPAG5 SPP1 TERF1 TINF2 TRIM23 TRIM27 TRIM39 USP9X ZBTB5	44 interacting genes: AMOTL2 ARNT2 ATN1 BARD1 C1orf109 CCDC33 CCHCR1 CDC20B CDK1 CHCHD3 DCX EIF4E2 EIF4ENIF1 ENKD1 FBXO28 FMR1 GOLGA8EP GOLGA8F HAUS1 IQCE KANSL1 LGALS14 LINGO1 MID1 MID2 NLGN3 ODF1 ORC6 PIMREG POLR2L RBM41 SH2D4A SMARCE1 SNAP47 SNAPIN TSHZ3 TTC23 ZC2HC1C ZFC3H1 ZFYVE26 ZGPAT ZMAT2 ZNF385C ZNF688
Entrez ID		1641	10615
HPRD ID		02127	10246
Ensembl ID		ENSG00000077279	ENSG00000076382
Uniprot IDs		A8K340 O43602	Q96R06
PDB IDs		1MJD 2BQQ 2XRP 4ATU 5IKC 5IN7 5IO9 5IOI 5IP4 6FNZ
Enriched GO Terms of Interacting Partners?
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