CNST and GJB2

Number of citations of the paper that reports this interaction (PubMedID 19864490)
17

Data Source:
BioGRID (pull down)

		CNST	GJB2
Description		consortin, connexin sorting protein	gap junction protein beta 2
Image		No pdb structure
GO Annotations	Cellular Component	Trans-Golgi Network Plasma Membrane Membrane Integral Component Of Membrane Transport Vesicle Protein-containing Complex Intracellular Membrane-bounded Organelle	Endoplasmic Reticulum-Golgi Intermediate Compartment Cytosol Plasma Membrane Integral Component Of Plasma Membrane Gap Junction Connexin Complex Lateral Plasma Membrane Cell Body Perinuclear Region Of Cytoplasm Astrocyte Projection
	Molecular Function	Protein Binding Phosphatase Binding Connexin Binding	Gap Junction Channel Activity Calcium Ion Binding Identical Protein Binding Gap Junction Channel Activity Involved In Cell Communication By Electrical Coupling
	Biological Process	Negative Regulation Of Phosphatase Activity Positive Regulation Of Golgi To Plasma Membrane Protein Transport	Response To Ischemia Cell-cell Signaling Aging Sensory Perception Of Sound Cell Communication By Electrical Coupling Gap Junction Assembly Response To Estradiol Response To Lipopolysaccharide Response To Retinoic Acid Response To Progesterone Cellular Response To Oxidative Stress Response To Human Chorionic Gonadotropin Response To Antibiotic Decidualization Inner Ear Development Transmembrane Transport Cellular Response To Glucagon Stimulus Cellular Response To Dexamethasone Stimulus Epididymis Development Gap Junction-mediated Intercellular Transport
Pathways			Oligomerization of connexins into connexons Transport of connexins along the secretory pathway Gap junction assembly Transport of connexons to the plasma membrane
Drugs
Diseases			Keratitis-ichthyosis-deafness syndrome Palmoplantar keratoderma with deafness Deafness, autosomal dominant Deafness, autosomal recessive Vohwinkel syndrome, including: Vohwinkel syndrome (VS); Vohwinkel syndrome with ichthyosis
GWAS		Antisaccade task score ( 31596458)	Facial emotion recognition (happy faces) ( 28608620)
Interacting Genes		11 interacting genes: EWSR1 GJA1 GJB1 GJB2 GJB3 GJB6 GJC1 POT1 PPP1CA PPP1CC ROPN1	8 interacting genes: CAV1 CD14 CNST CREB3 GJB1 GJB6 LMNA NGLY1
Entrez ID		163882	2706
HPRD ID		08718	00413
Ensembl ID		ENSG00000162852	ENSG00000165474
Uniprot IDs		Q6PJW8	H9U1J4 P29033
PDB IDs			1XIR 2ZW3 3IZ1 3IZ2 5ER7 5ERA 5KJ3 5KJG
Enriched GO Terms of Interacting Partners?
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