DAXX and AIRE

  • Number of citations of the paper that reports this interaction (PubMedID 20185822)
  • 10
  • Data Source:
  • BioGRID (two hybrid, affinity chromatography technology)

DAXX

AIRE

Description death domain associated protein autoimmune regulator
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Disrupted circadian rhythm (low relative amplitude of rest-activity cycles) ( 30120083)
  • Lung cancer ( 28604730)
  • Lung cancer in ever smokers ( 28604730)
Interacting Genes 91 interacting genes: ACVR2A AIRE AR ATM ATRX BTBD6 CA12 CALCOCO2 CARD9 CARM1 CBS CDCA7L CENPC CFLAR CREBBP CSNK2A1 DAPK3 DKC1 DMAP1 DNMT1 ESRRG ETS1 FAM9B FANCA FAS FASLG FTH1 GOLGA2 H3C3 H4-16 H4C6 HABP4 HBA1 HDAC1 HDAC2 HDAC3 HIPK1 HIPK2 HIPK3 HSF1 HSF4 HSPB1 MAP3K5 MCRS1 MDM2 MEN1 MX1 MYH11 NECAB2 NSD3 PARK7 PAX3 PAX5 PBXIP1 PLAGL1 PML PNMA1 PRMT1 PTEN RASSF1 RIPK3 RPL13 SENP2 SERBP1 SLC2A4 SLC9A1 SNW1 SPN SPOP SSX2IP STAT3 STK4 STUB1 SUMO1 SUMO2 SUMO3 TCF3 TCF4 TCF7L2 TGFB1 TGFBR2 TNFRSF1A TP53 TP63 TP73 TRAF3 TRIM21 TSG101 UBC UBE2I USP7 5 interacting genes: CREBBP DAXX H2BC21 H3C1 UBAC1
Entrez ID 1616 326
HPRD ID 04424 06301
Ensembl ID ENSG00000204209 ENSG00000160224
Uniprot IDs A0A024RCS3 B4E1C1 Q53F85 Q9UER7 O43918
PDB IDs 2KQS 2KZS 2KZU 4H9N 4H9O 4H9P 4H9Q 4H9R 4H9S 4HGA 5GRQ 5KDM 5Y18 5Y6O 1XWH 2KE1 2KFT 2LRI
Enriched GO Terms of Interacting Partners?
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