TAMALIN and GRM3

Number of citations of the paper that reports this interaction (PubMedID 11850456)
62

Data Source:
HPRD (two hybrid)

		TAMALIN	GRM3
Description		trafficking regulator and scaffold protein tamalin	glutamate metabotropic receptor 3
Image
GO Annotations	Cellular Component	Plasma Membrane Postsynaptic Density Cell Junction Postsynaptic Membrane Perinuclear Region Of Cytoplasm Schaffer Collateral - CA1 Synapse Glutamatergic Synapse	Plasma Membrane Integral Component Of Plasma Membrane Postsynaptic Density Axon Dendritic Spine Glutamatergic Synapse Integral Component Of Postsynaptic Membrane Integral Component Of Presynaptic Membrane
	Molecular Function	PDZ Domain Binding ADP-ribosylation Factor Binding Identical Protein Binding	Group II Metabotropic Glutamate Receptor Activity G Protein-coupled Receptor Activity Calcium Channel Regulator Activity Glutamate Receptor Activity
	Biological Process	Signal Transduction Protein Localization Regulation Of Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane	G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity Adenylate Cyclase-inhibiting G Protein-coupled Glutamate Receptor Signaling Pathway G Protein-coupled Glutamate Receptor Signaling Pathway Chemical Synaptic Transmission Regulation Of Synaptic Transmission, Glutamatergic
Pathways			G alpha (i) signalling events Class C/3 (Metabotropic glutamate/pheromone receptors)
Drugs			LY2140023
Diseases
GWAS			anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Asthma ( 27611488) Autism spectrum disorder or schizophrenia ( 28540026) Brachial circumference ( 22479309) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Feeling worry ( 29500382) Neurociticism ( 29500382) Neuroticism ( 29255261) Schizophrenia ( 28991256 25056061 29483656 30285260) Seborrheic dermatitis ( 29203360) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		11 interacting genes: CYTH3 DLG4 DOCK1 FYN GABBR2 GRM1 GRM2 GRM3 GRM5 RPS6KA1 SRC	6 interacting genes: CALM1 GRIP1 PICK1 PPM1A SDCBP TAMALIN
Entrez ID		160622	2913
HPRD ID		17077	03070
Ensembl ID		ENSG00000161835	ENSG00000198822
Uniprot IDs		Q7Z6J2	A4D1D0 Q14832
PDB IDs		2PNT	1S8M 3SM9 4XAR 5CNK 5CNM 6B7H
Enriched GO Terms of Interacting Partners?
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