GRK2 and CCR5

  • Number of citations of the paper that reports this interaction (PubMedID 10085131)
  • 39
  • Data Source:
  • HPRD (in vivo)

GRK2

CCR5

Description G protein-coupled receptor kinase 2 C-C motif chemokine receptor 5 (gene/pseudogene)
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood protein levels ( 28240269)
  • Blood protein levels in cardiovascular risk ( 28369058)
  • Celiac disease ( 20190752)
  • Cerebrospinal fluid levels of Alzheimer's disease-related proteins ( 25340798)
  • Granulocyte percentage of myeloid white cells ( 27863252)
  • Inflammatory bowel disease ( 26192919)
  • Type 1 diabetes ( 25751624)
  • Ulcerative colitis ( 26192919 28067908)
Interacting Genes 50 interacting genes: ADRA2A ADRB2 AGTR1 AKAP12 ARRB1 ARRB2 BDKRB2 CAPN2 CAV1 CCR4 CCR5 CSNK2B EGF EGFR EPHA2 FBXO25 FPR1 FSHR GIT1 GIT2 GNA15 GNAQ GNB2 GNB3 GRM1 HDAC6 KCNIP3 MAPK3 MC4R MDM2 NCS1 OPRD1 PDC PDCL PDE6G PEBP1 PIK3CG PLCB1 PRKACA PRKCA PRKCB PRKCD PRKCG RASGRF1 RCVRN RHO RPLP2 SNCA SRC TPM2 41 interacting genes: AFP ARL6IP5 ARRB1 CCL11 CCL13 CCL14 CCL16 CCL2 CCL3 CCL3L1 CCL3L3 CCL4 CCL5 CCL7 CCL8 CD4 CST9L CTBP2 CXCR4 DNM2 ETV5 GNAI1 GNAI2 GNAI3 GNAO1 GNAQ GRK2 GRK3 IL24 JAK1 JAK2 LCK ORM1 PRAF2 PSMA5 PTK2 PTK2B STAT1 STAT3 STAT5A TXK
Entrez ID 156 1234
HPRD ID 00182 03223
Ensembl ID ENSG00000173020 ENSG00000160791
Uniprot IDs A0A0S2Z392 P25098 P51681 Q38L21
PDB IDs 1BAK 3CIK 3KRW 3KRX 3V5W 4MK0 4PNK 5HE1 5UKK 5UKL 5UUU 5UVC 5WG3 5WG4 5WG5 6C2Y 1ND8 1NE0 1OPN 1OPT 1OPW 2L87 2MZX 2RLL 2RRS 4MBS 5UIW 5YD3 5YD4 5YD5 5YY4 6FGP 6MEO 6MET
Enriched GO Terms of Interacting Partners?
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