SH3D19 and ADAM12

Number of citations of the paper that reports this interaction (PubMedID 15280379)
25

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		SH3D19	ADAM12
Description		SH3 domain containing 19	ADAM metallopeptidase domain 12
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane	Extracellular Region Nucleoplasm Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding	Metalloendopeptidase Activity Protein Binding Metallopeptidase Activity SH3 Domain Binding Metal Ion Binding
	Biological Process	Cytoskeleton Organization Regulation Of Cell Morphogenesis Positive Regulation Of Membrane Protein Ectodomain Proteolysis	Proteolysis Cell Adhesion Myoblast Fusion Extracellular Matrix Organization Positive Regulation Of Angiogenesis
Pathways		Golgi Associated Vesicle Biogenesis	Signaling by EGFR Invadopodia formation
Drugs
Diseases
GWAS			Blood protein levels ( 30072576) Endometrial cancer ( 24096698) Extremely high intelligence ( 29731509) Heel bone mineral density ( 30598549) Intraocular pressure ( 30054594) Itch intensity from mosquito bite ( 28199695) Loneliness ( 27629369) Metabolite levels (5-HIAA/ MHPG Ratio) ( 23319000) Mild influenza (H1N1) infection ( 26379185) Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 26184070 27021288) Placental abruption ( 29884306) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010) Visceral fat ( 22589738)
Interacting Genes		11 interacting genes: ADAM10 ADAM12 ADAM15 ADAM17 ADAM9 CDC42 GRB2 SH3GL1 SH3GL3 SH3YL1 SOS2	12 interacting genes: ACTN2 EGF FSTL3 GRB2 IGFBP3 IGFBP5 PACSIN3 PIK3R1 SH3D19 SRC TUBGCP2 YES1
Entrez ID		152503	8038
HPRD ID		16364	04092
Ensembl ID		ENSG00000109686	ENSG00000148848
Uniprot IDs		A0A494C1M0 Q5HYK7	A8K6G4 O43184 U5NE98
PDB IDs
Enriched GO Terms of Interacting Partners?
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