ALG10B and ANO6

		ALG10B	ANO6
Description		ALG10 alpha-1,2-glucosyltransferase B	anoctamin 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Integral Component Of Membrane	Cell Cytosol Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Membrane Chloride Channel Complex Specific Granule Membrane Extracellular Exosome Tertiary Granule Membrane
	Molecular Function	Dolichyl-phosphate-glucose-glycolipid Alpha-glucosyltransferase Activity Transferase Activity Dolichyl Pyrophosphate Glc2Man9GlcNAc2 Alpha-1,2-glucosyltransferase Activity	Calcium Activated Cation Channel Activity Intracellular Calcium Activated Chloride Channel Activity Voltage-gated Ion Channel Activity Voltage-gated Chloride Channel Activity Protein Binding Phospholipid Scramblase Activity Protein Homodimerization Activity Metal Ion Binding
	Biological Process	Protein Glycosylation Dolichol-linked Oligosaccharide Biosynthetic Process Positive Regulation Of Protein Glycosylation Positive Regulation Of Inward Rectifier Potassium Channel Activity	Dendritic Cell Chemotaxis Activation Of Blood Coagulation Via Clotting Cascade Cation Transport Chloride Transport Blood Coagulation Phospholipid Scrambling Positive Regulation Of Bone Mineralization Bleb Assembly Ion Transmembrane Transport Positive Regulation Of Ion Transmembrane Transport Purinergic Nucleotide Receptor Signaling Pathway Bone Mineralization Involved In Bone Maturation Sodium Ion Transmembrane Transport Positive Regulation Of Apoptotic Process Neutrophil Degranulation Negative Regulation Of Cell Volume Pore Complex Assembly Positive Regulation Of Phagocytosis, Engulfment Calcium Activated Phosphatidylserine Scrambling Calcium Activated Phosphatidylcholine Scrambling Calcium Activated Galactosylceramide Scrambling Calcium Ion Transmembrane Transport Positive Regulation Of Monocyte Chemotaxis Phosphatidylserine Exposure On Blood Platelet Chloride Transmembrane Transport Positive Regulation Of Potassium Ion Export Across Plasma Membrane Positive Regulation Of Endothelial Cell Apoptotic Process
Pathways		Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein	Stimuli-sensing channels Neutrophil degranulation
Drugs
Diseases
GWAS		Chronotype ( 30696823) Drug-induced liver injury (flucloxacillin) ( 19483685) Heart rate response to recovery post exercise ( 29769521) Idiopathic dilated cardiomyopathy ( 29495422) Morning person ( 30696823) Morning vs. evening chronotype ( 26835600) Resting heart rate ( 27798624)	Ankylosing spondylitis ( 22138694) Insomnia ( 29520036) Urate levels in obese individuals ( 25811787) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		2 interacting genes: ANO6 KCNH2	9 interacting genes: ALG10B ARID2 C12orf40 CPNE8 GXYLT1 LRRK2 MUC19 PRICKLE1 SLC2A13
Entrez ID		144245	196527
HPRD ID		11923	18746
Ensembl ID		ENSG00000175548	ENSG00000177119
Uniprot IDs		Q5I7T1	B3KX12 Q4KMQ2
PDB IDs
Enriched GO Terms of Interacting Partners?
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