RALYL and THAP1

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
HPRD (two hybrid)

		RALYL	THAP1
Description		RALY RNA binding protein like	THAP domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nuclear Chromatin Fibrillar Center Nucleus Nucleoplasm PML Body Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Binding Protein Binding Identical Protein Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Zinc Ion Binding Identical Protein Binding Protein Homodimerization Activity Sequence-specific DNA Binding
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Endothelial Cell Proliferation Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Cycle Regulation Of Mitotic Cell Cycle
Pathways
Drugs
Diseases			Primary torsion dystonia (PTD)
GWAS		Body mass index ( 28892062 25673413) Depressive symptoms x independent stressful life events interaction (1df test) ( 30718454) Depressive symptoms x independent stressful life events interaction (2df test) ( 30718454) Diastolic blood pressure ( 27841878) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Night sleep phenotypes ( 27126917) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Systolic blood pressure ( 27841878) Trunk fat mass ( 28552196)	Pelvic organ prolapse (moderate/severe) ( 26545240)
Interacting Genes		17 interacting genes: AEBP2 AEN BYSL C20orf27 CCDC85B CEP170P1 EWSR1 FXR2 HNRNPC LMO3 LRRK2 MCRS1 PSMF1 RBM41 THAP1 TSNAX ZNF408	65 interacting genes: ABCF3 ACOT7 AEBP2 AKAP17A AKAP9 AP2B1 APP ARL6IP4 BAG5 BMS1P1 BYSL C1orf35 C7orf50 CHD2 CSNK2A1 DCAF8 DVL2 EEF1AKNMT FAM124A FAM133A FXR2 GOLGA7 GPATCH2L HNRNPLL KLF12 KRTAP10-7 LASP1 MORF4L1 MORF4L2 MRPL11 NKAP NKAPD1 NTAQ1 NUP62 PAWR PHF1 PID1 POLR2L POLR2M PPIG PRKAA1 PRR20A QKI RALYL RBM10 RBM39 RIPPLY1 RP9P RPS25 SAP30BP SERF2 SLU7 STRBP TCEA2 TPM3 TRAF5 TRIM26 TTLL10 TXN2 U2AF2 WT1 YES1 ZCCHC10 ZNF385C ZNF408
Entrez ID		138046	55145
HPRD ID		11236	15496
Ensembl ID		ENSG00000184672	ENSG00000131931
Uniprot IDs		B3KT61 Q86SE5	Q9NVV9
PDB IDs			2JTG 2KO0 2L1G
Enriched GO Terms of Interacting Partners?
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