CLDN3 and CLDN5

Number of citations of the paper that reports this interaction (PubMedID 12909588)
91

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		CLDN3	CLDN5
Description		claudin 3	claudin 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Integral Component Of Plasma Membrane Cell-cell Junction Bicellular Tight Junction Integral Component Of Membrane Apicolateral Plasma Membrane Lateral Plasma Membrane Protein-containing Complex Apical Junction Complex Tight Junction	Plasma Membrane Cell-cell Junction Bicellular Tight Junction Integral Component Of Membrane Apicolateral Plasma Membrane Cell Junction Cortical Actin Cytoskeleton Tight Junction
	Molecular Function	Transmembrane Signaling Receptor Activity Structural Molecule Activity Protein Binding Identical Protein Binding	Structural Molecule Activity Protein Binding Identical Protein Binding
	Biological Process	Response To Hypoxia Positive Regulation Of Protein Phosphorylation Epithelial Cell Morphogenesis Negative Regulation Of Cell Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Establishment Of Endothelial Blood-brain Barrier Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Regulation Of Cell Morphogenesis Positive Regulation Of Cell Migration Negative Regulation Of Cell Migration Actin Cytoskeleton Reorganization Cell Junction Maintenance Response To Ethanol Negative Regulation Of Wound Healing Bicellular Tight Junction Assembly Positive Regulation Of Wound Healing Regulation Of Membrane Permeability Positive Regulation Of Cell Junction Assembly Positive Regulation Of Bicellular Tight Junction Assembly Positive Regulation Of Metallopeptidase Activity	Outflow Tract Morphogenesis Cell-cell Junction Assembly Transforming Growth Factor Beta Receptor Signaling Pathway Learning Positive Regulation Of Cell Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Negative Regulation Of Angiogenesis Negative Regulation Of Cell Migration Positive Regulation Of Protein Binding Maintenance Of Permeability Of Blood-brain Barrier Negative Regulation Of Vascular Permeability Roof Of Mouth Development Face Morphogenesis Tight Junction Assembly Positive Regulation Of Establishment Of Endothelial Barrier Positive Regulation Of Bicellular Tight Junction Assembly Establishment Of Blood-retinal Barrier Regulation Of Bicellular Tight Junction Assembly
Pathways		Tight junction interactions	Tight junction interactions RUNX1 regulates expression of components of tight junctions
Drugs
Diseases
GWAS		Mean platelet volume ( 27863252) Platelet distribution width ( 27863252)
Interacting Genes		7 interacting genes: APP CLDN1 CLDN5 POM121 PRKACA TJP1 WNK4	3 interacting genes: CLDN3 MPDZ TJP1
Entrez ID		1365	7122
HPRD ID		04219	03654
Ensembl ID		ENSG00000165215	ENSG00000184113
Uniprot IDs		O15551 Q75L79	D3DX19 O00501
PDB IDs
Enriched GO Terms of Interacting Partners?
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