CPE and CCK

Number of citations of the paper that reports this interaction (PubMedID 9275097)
10

Data Source:
HPRD (in vivo)

		CPE	CCK
Description		carboxypeptidase E	cholecystokinin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Golgi Apparatus Plasma Membrane Transport Vesicle Membrane Secretory Granule Membrane Extracellular Exosome	Extracellular Region Extracellular Space Axon Dendrite Axon Initial Segment Terminal Bouton Axon Hillock Perikaryon
	Molecular Function	Carboxypeptidase Activity Metallocarboxypeptidase Activity Zinc Ion Binding Neurexin Family Protein Binding Cell Adhesion Molecule Binding	Hormone Activity Neuropeptide Hormone Activity Peptide Hormone Receptor Binding
	Biological Process	Cardiac Left Ventricle Morphogenesis Cellular Protein Modification Process Peptide Metabolic Process Neuropeptide Signaling Pathway Wnt Signaling Pathway Protein Processing Insulin Processing Peptide Hormone Secretion Protein Localization To Secretory Granule Protein Localization To Membrane	Neuron Migration Release Of Cytochrome C From Mitochondria Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Signal Transduction G Protein-coupled Receptor Signaling Pathway Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Axonogenesis Digestion Memory Positive Regulation Of Cell Proliferation Visual Learning Positive Regulation Of Glutamate Secretion Positive Regulation Of Protein Complex Assembly Negative Regulation Of Appetite Eating Behavior Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Mitochondrial Depolarization Negative Regulation Of Eating Behavior Positive Regulation Of Sensory Perception Of Pain Negative Regulation Of Behavioral Fear Response Positive Regulation Of Behavioral Fear Response
Pathways		Insulin processing	Peptide ligand-binding receptors G alpha (q) signalling events
Drugs		Insulin Human Insulin Pork
Diseases
GWAS		Pelvic organ prolapse (moderate/severe) ( 26545240) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)	Body mass index ( 24348519 28892062 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (SNP x SNP interaction) ( 22344221) Night sleep phenotypes ( 27126917)
Interacting Genes		17 interacting genes: BDNF CCK CHD3 GAST GCG GTF3C1 INS LRIF1 MED31 NTS PMCH POLA2 POLDIP2 ROBO2 RPA1 TRH UTP14A	6 interacting genes: CCKAR CCKBR CPE ENPEP MEP1A MEP1B
Entrez ID		1363	885
HPRD ID		00272	00321
Ensembl ID		ENSG00000109472	ENSG00000187094
Uniprot IDs		A0A384N679 P16870	P06307 Q6FG82
PDB IDs
Enriched GO Terms of Interacting Partners?
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